| Literature DB >> 30709509 |
Courtney M Rowan1, Sophie Paczesny2.
Abstract
Advances in the field of omics have led to a significant expansion in biomarkers identified for complications after hematopoietic stem cell transplantation (HSCT). Biomarkers can offer an effective method for early identification of a specific disease and can be used to guide therapies. Ongoing investigations to discover biomarkers for acute graft-versus-host disease as well as other post-HSCT complications may improve early diagnosis, prognosis, and the development of new therapeutic targets. The authors review the most recent and validated diagnostic, prognostic, predictive, and response to treatment biomarkers for early complications following HSCT consistent with 2014 NIH consensus on biomarker criteria.Entities:
Keywords: Biomarkers; Graft versus host disease; Hematopoietic stem cell transplantation; Proteomics
Mesh:
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Year: 2018 PMID: 30709509 PMCID: PMC7138508 DOI: 10.1016/j.cll.2018.10.005
Source DB: PubMed Journal: Clin Lab Med ISSN: 0272-2712 Impact factor: 1.935