Literature DB >> 30707547

Facts, Results, and Perspectives of the Current Alzheimer's Disease Research.

José Marco-Contelles1.   

Abstract

Credit should be granted to medicinal chemists with a solid background in organic chemistry and computational chemistry, able to read, understand, and discuss the biological data, in order to design new and more efficient therapeutic approaches for Alzheimer's disease.

Entities:  

Keywords:  Alzheimer’s disease; Aβ hypothesis; disease-modifying therapy approach; multitarget small molecules; symptomatic-disease approach; tau hypothesis

Mesh:

Substances:

Year:  2019        PMID: 30707547     DOI: 10.1021/acschemneuro.9b00034

Source DB:  PubMed          Journal:  ACS Chem Neurosci        ISSN: 1948-7193            Impact factor:   4.418


  4 in total

1.  "AβTau", Lobby or Religion?

Authors:  José Marco-Contelles
Journal:  ACS Med Chem Lett       Date:  2019-09-25       Impact factor: 4.345

Review 2.  Perspectives for New and More Efficient Multifunctional Ligands for Alzheimer's Disease Therapy.

Authors:  Agnieszka Zagórska; Anna Jaromin
Journal:  Molecules       Date:  2020-07-23       Impact factor: 4.411

3.  Novel tacrine-benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer's Disease.

Authors:  Gaia Fancellu; Karam Chand; Daniel Tomás; Elisabetta Orlandini; Luca Piemontese; Diana F Silva; Sandra M Cardoso; Sílvia Chaves; M Amélia Santos
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051

4.  Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.

Authors:  Sílvia Chaves; Simonetta Resta; Federica Rinaldo; Marina Costa; Romane Josselin; Karolina Gwizdala; Luca Piemontese; Vito Capriati; A Raquel Pereira-Santos; Sandra M Cardoso; M Amélia Santos
Journal:  Molecules       Date:  2020-02-22       Impact factor: 4.411

  4 in total

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