| Literature DB >> 30706252 |
Yu-Shao Chou1,2, Hsin-Yueh Lin1,2, Yi-Ming Weng3, Zhong Ning Leonard Goh4, Cheng-Yu Chien5, Hsuan-Jui Fan1,2, Chih-Huang Li1,2, Hsien-Yi Chen1,2, Ming-Shun Hsieh6,7,8, Joanna Chen-Yeen Seak9, Chen-Ken Seak9, Chen-June Seak10,11,12.
Abstract
Percutaneous coronary interventions (PCIs) within a door-to-balloon timing of 90 min have greatly decreased mortality and morbidity of ST-elevation myocardial infarction (STEMI) patients. Post-PCI, they are routinely transferred into the coronary care unit (CCU) regardless of the severity of their condition, resulting in frequent CCU overcrowding. This study assesses the feasibility of step-down units (SDUs) as an alternative to CCUs in the management of STEMI patients after successful PCI, to alleviate CCU overcrowding. Criteria of assessment include in-hospital complications, length of stay, cost-effectiveness, and patient outcomes up to a year after discharge from hospital. A retrospective case-control study was done using data of 294 adult STEMI patients admitted to the emergency departments of two training and research hospitals and successfully underwent primary PCI from 1 January 2014 to 31 December 2015. Patients were followed up for a year post-discharge. Student t test and χ2 test were done as univariate analysis to check for statistical significance of p < 0.05. Further regression analysis was done with respect to primary outcomes to adjust for major confounders. Patients managed in the SDU incurred significantly lower inpatient costs (p = 0.0003). No significant differences were found between the CCU and SDU patients in terms of patient characteristics, PCI characteristics, in-hospital complications, length of stay, and patient outcomes up to a year after discharge. The SDU is a viable cost-effective option for managing STEMI patients after successful primary PCI to avoid CCU overcrowding, with non-inferior patient outcomes as compared to the CCU.Entities:
Keywords: Coronary care unit; Cost analysis; ST-elevation myocardial infarction; Step-down unit
Mesh:
Year: 2019 PMID: 30706252 DOI: 10.1007/s11739-019-02037-z
Source DB: PubMed Journal: Intern Emerg Med ISSN: 1828-0447 Impact factor: 3.397