| Literature DB >> 30705787 |
Anitha P Ambika1, Sreesha N Nair1.
Abstract
Significance: Compounds derived from plants are gaining importance for the treatment of several diseases. Many plants from the Convolvulaceae family contain compounds that have demonstrated wound healing and antidiabetic activity. Such compounds can be effectively used as a part of treatments to promote wound healing in diabetics and used in combination with antimicrobial therapy to reduce the likelihood of drug resistance and allergic reactions. Novel strategies for developing herbal formulations such as nanoparticles and adhesive patches can improve the delivery of plant-based therapeutic agents. Recent Advances: Studies have confirmed the antidiabetic and wound healing activities of Merremia tridentata, Argyreia speciosa, and Ipomoea batatas, whereas Evolvulus alsinoides, Evolvulus nummularius, Argyreia cuneata, and Ipomoea carnea have wound healing activity. Critical Issues: Drug resistance is a major problem associated with antimicrobial therapy and can affect wound healing processes. Phytoconstituents can facilitate healing processes and reduce reliance on antibiotics. Future Directions: Plants from the Convolvulaceae family have had frequent traditional uses, and all plants selected for this study have antimicrobial, antidiabetic, and wound healing properties. Detailed phytochemical studies of these plants can help develop novel wound healing therapies.Entities:
Keywords: adhesive patches; antidiabetic; drug resistance; nanoparticle; wound healing activity
Year: 2019 PMID: 30705787 PMCID: PMC6350056 DOI: 10.1089/wound.2017.0781
Source DB: PubMed Journal: Adv Wound Care (New Rochelle) ISSN: 2162-1918 Impact factor: 4.730