Hesham Elsharkawy1, Ilker Ince2, Amit Pawa3. 1. Department of General Anesthesia and Pain Management, Anesthesiology Institute, USA; CCLCM of Case Western Reserve University, Cleveland Clinic, 9500 Euclid Avenue, Mail Code E31, Cleveland, OH, 44195, USA. Electronic address: elsharh@ccf.org. 2. Department of Anesthesiology and Reanimation, School of Medicine, Ataturk University, TR-25240 Erzurum, Turkey; Anesthesiology Institute Outcomes Research Department, Cleveland Clinic, Cleveland, OH, USA. Electronic address: incei@ccf.org. 3. Guy's & St Thomas' NHS Foundation Trust, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.