| Literature DB >> 30703171 |
Reham Shehabeldin, David Lutz, Meliha Karsak, Michael Frotscher, Kerstin Krieglstein, Ahmed Sharaf.
Abstract
[This corrects the article DOI: 10.1371/journal.pone.0200268.].Entities:
Year: 2019 PMID: 30703171 PMCID: PMC6355025 DOI: 10.1371/journal.pone.0211849
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 7Altered serotonergic innervation of the reeler hippocampus at P20.
(A) Expression of Cxcr4-eGFP in Cajal-Retzius (CR) cells of the dentate gyrus. (B-D) Serotonergic fibers are distributed throughout hippocampal layers, and 5-HT positive fibers and Cajal-Retzius cells overlap. (E) Scattered distribution of Cajal-Retzius cells in reeler hippocampus. (F-H) Severe reduction of serotonergic fibers in Cxcr4-eGFP hippocampal reeler mice. CA1, cornu ammonis area 1; CA3, cornu ammonis area 3; DG, dentate gyrus. Scale bar for A-D: 100μm.
Fig 10Reduction of serotonin transporter protein (SERT) expression in brain regions of reeler mice.
A. Western blot analysis showed reduction of SERT protein levels in reeler cortex, hippocampus, and Cerebellum as compared to wild type. (B-G) reduction of SERT expression in reeler cortex as well as in hippocampal slices as observed in (H-M) as compared to the same matched wild type littermates at P30. Hippo = hippocampus; Cereb = Cerebellum. Scale bar: 100 μm.