BACKGROUND: Radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) can be curative. There are conflicting data on whether AF associated atrial and ventricular structural remodeling reverses after ablation. The aim of this study was to evaluate the hemodynamic effect of AF ablation in patients with preserved left ventricular ejection fraction (LVEF). METHODS: Forty three AF patients were studied (aged 56 ± 11 years; 29 male, 23% persistent AF, LVEF ≥ 50%) in whom RFCA was performed. Echocardiographic evaluation of atrial and ventricular diameters, volumes and strain imaging by two-dimensional speckle tracking were performed before and at least 6 months after RFCA. Nine patients had AF during baseline examination. RESULTS: A significant decrease in the left (LA) and right (RA) atrial volume and an increase in the LA strain were observed 15 ± 7 months after RFCA. In the subgroup with baseline sinus rhythm, the increment in LA strain was only borderline significant. An increase in RA, right ventricular (RV) and Biatrial strain was noticed (p < 0.05). LVEF and global longitudinal strain of the left ventricle (LV), however, did not improve substantially. CONCLUSIONS: Radiofrequency catheter ablation of AF in patients with preserved LV systolic function results in significant improvement in RA and RV function with a substantial reduction in LA and RA size. No deleterious impact of AF ablation on LA function was revealed.
BACKGROUND: Radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) can be curative. There are conflicting data on whether AF associated atrial and ventricular structural remodeling reverses after ablation. The aim of this study was to evaluate the hemodynamic effect of AF ablation in patients with preserved left ventricular ejection fraction (LVEF). METHODS: Forty three AFpatients were studied (aged 56 ± 11 years; 29 male, 23% persistent AF, LVEF ≥ 50%) in whom RFCA was performed. Echocardiographic evaluation of atrial and ventricular diameters, volumes and strain imaging by two-dimensional speckle tracking were performed before and at least 6 months after RFCA. Nine patients had AF during baseline examination. RESULTS: A significant decrease in the left (LA) and right (RA) atrial volume and an increase in the LA strain were observed 15 ± 7 months after RFCA. In the subgroup with baseline sinus rhythm, the increment in LA strain was only borderline significant. An increase in RA, right ventricular (RV) and Biatrial strain was noticed (p < 0.05). LVEF and global longitudinal strain of the left ventricle (LV), however, did not improve substantially. CONCLUSIONS: Radiofrequency catheter ablation of AF in patients with preserved LV systolic function results in significant improvement in RA and RV function with a substantial reduction in LA and RA size. No deleterious impact of AF ablation on LA function was revealed.
Authors: Agnes Pump; Luigi Di Biase; Justin Price; Prasant Mohanty; Rong Bai; Pasquale Santangeli; Sanghamitra Mohanty; Chintan Trivedi; Rachel Xue Yan; Rodney Horton; Javier E Sanchez; Jason Zagrodzky; Shane Bailey; G Joseph Gallinghouse; J David Burkhardt; Andrea Natale Journal: J Cardiovasc Electrophysiol Date: 2013-09-10
Authors: Roberto M Lang; Luigi P Badano; Victor Mor-Avi; Jonathan Afilalo; Anderson Armstrong; Laura Ernande; Frank A Flachskampf; Elyse Foster; Steven A Goldstein; Tatiana Kuznetsova; Patrizio Lancellotti; Denisa Muraru; Michael H Picard; Ernst R Rietzschel; Lawrence Rudski; Kirk T Spencer; Wendy Tsang; Jens-Uwe Voigt Journal: Eur Heart J Cardiovasc Imaging Date: 2015-03 Impact factor: 6.875
Authors: Faraz Pathan; Nicholas D'Elia; Mark T Nolan; Thomas H Marwick; Kazuaki Negishi Journal: J Am Soc Echocardiogr Date: 2016-10-27 Impact factor: 5.251
Authors: Luigi P Badano; Theodore J Kolias; Denisa Muraru; Theodore P Abraham; Gerard Aurigemma; Thor Edvardsen; Jan D'Hooge; Erwan Donal; Alan G Fraser; Thomas Marwick; Luc Mertens; Bogdan A Popescu; Partho P Sengupta; Patrizio Lancellotti; James D Thomas; Jens-Uwe Voigt Journal: Eur Heart J Cardiovasc Imaging Date: 2018-06-01 Impact factor: 6.875
Authors: John V Wylie; Dana C Peters; Vidal Essebag; Warren J Manning; Mark E Josephson; Thomas H Hauser Journal: Heart Rhythm Date: 2008-02-08 Impact factor: 6.343