Literature DB >> 30698457

Risk factors for surgical site infections in neurosurgery.

S Patel1, D Thompson1, S Innocent2, V Narbad1, R Selway1, K Barkas1.   

Abstract

INTRODUCTION: Surgical site infections (SSIs) are of profound significance in neurosurgical departments, resulting in high morbidity and mortality. There are limited public data regarding the incidence of SSIs in neurosurgery. The aim of this study was to determine the rate of SSIs (particularly those requiring reoperation) over a seven-year period and identify factors leading to an increased risk.
METHODS: An age matched retrospective analysis was undertaken of a series of 16,513 patients at a single centre. All patients who required reoperation for suspected SSIs within a 7-year period were identified. Exclusion criteria comprised absence of infective material intraoperatively and patients presenting with primary infections. Clinical notes were reviewed to confirm presence or absence of suspected risk factors.
RESULTS: Of the 16,513 patients in the study, 1.20% required at least one further operation to treat a SSI. Wound leak (odds ratio [OR]: 27.41), dexamethasone use (OR: 3.55), instrumentation (OR: 2.74) and operative duration >180 minutes (OR: 1.85) were statistically significant risk factors for reoperation.
CONCLUSIONS: This is the first UK study of such a duration that has documented a SSI reoperation rate in a cohort of this size. Various risk factors are associated with the development of SSIs, making it essential to have robust auditing and monitoring of high risk patients to ensure excellent standards of healthcare. Departmental and public registers to record all SSIs may be beneficial, particularly for those treated solely by general practitioners, allowing units to address potential risk factors prior to surgical intervention.

Entities:  

Keywords:  Risk factors; Surgical site infection; Wound infection; Wound leak

Mesh:

Substances:

Year:  2019        PMID: 30698457      PMCID: PMC6400918          DOI: 10.1308/rcsann.2019.0001

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  21 in total

1.  Relationship between skin microbial counts and surgical site infection after neurosurgery.

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Review 2.  Contributing factors to surgical site infections.

Authors:  James S Harrop; John C Styliaras; Yinn Cher Ooi; Kristen E Radcliff; Alexander R Vaccaro; Chengyuan Wu
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3.  Does chlorhexidine and povidone-iodine preoperative antisepsis reduce surgical site infection in cranial neurosurgery?

Authors:  B M Davies; H C Patel
Journal:  Ann R Coll Surg Engl       Date:  2016-04-08       Impact factor: 1.891

4.  Risk factors for the development of delayed infections following posterior spinal fusion and instrumentation in adolescent idiopathic scoliosis patients.

Authors:  Christine Ho; Daniel J Sucato; B Stephens Richards
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5.  Risk factors for surgical site infection following orthopaedic spinal operations.

Authors:  Margaret A Olsen; Jeffrey J Nepple; K Daniel Riew; Lawrence G Lenke; Keith H Bridwell; Jennie Mayfield; Victoria J Fraser
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Review 6.  Corticosteroids and wound healing: clinical considerations in the perioperative period.

Authors:  Audrey S Wang; Ehrin J Armstrong; April W Armstrong
Journal:  Am J Surg       Date:  2013-06-04       Impact factor: 2.565

7.  Implementation of a care bundle and evaluation of risk factors for surgical site infection in cranial neurosurgery.

Authors:  Benjamin M Davies; Anna Jones; Hiren C Patel
Journal:  Clin Neurol Neurosurg       Date:  2016-03-29       Impact factor: 1.876

8.  Analysis of matched case-control studies.

Authors:  Neil Pearce
Journal:  BMJ       Date:  2016-02-25

9.  The incidence and risk factors for surgical site infection after clean spinal operations: A prospective cohort study and review of the literature.

Authors:  Saeed Saeedinia; Mohsen Nouri; Amir Azarhomayoun; Hamed Hanif; Abolghasem Mortazavi; Parisa Bahramian; Kourosh Karimi Yarandi; Abbas Amirjamshidi
Journal:  Surg Neurol Int       Date:  2015-09-29

10.  Infection with spinal instrumentation: Review of pathogenesis, diagnosis, prevention, and management.

Authors:  Manish K Kasliwal; Lee A Tan; Vincent C Traynelis
Journal:  Surg Neurol Int       Date:  2013-10-29
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  1 in total

1.  Pre-Emptive Incision-Site Infiltration with Ropivacaine Plus Dexamethasone for Postoperative Pain After Supratentorial Craniotomy: A Prospective Randomized Controlled Trial.

Authors:  Chunmei Zhao; Shaoheng Wang; Yuesong Pan; Nan Ji; Fang Luo
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  1 in total

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