Literature DB >> 30696926

Effect of electrical stimulation on muscle atrophy and spasticity in patients with spinal cord injury - a systematic review with meta-analysis.

Sergio Ricardo Thomaz1, Gerson Cipriano2, Magno Ferreira Formiga3, Emerson Fachin-Martins2, Graziella França Bernardelli Cipriano4,2, Wagner Rodrigues Martins2, Lawrence Patrick Cahalin3.   

Abstract

STUDY
DESIGN: This work is a systematic review with meta-analysis
OBJECTIVE: Evaluate the effect of electrical stimulation (ES) on skeletal muscle volume and spasticity in individuals with spinal cord injury (SCI).
SETTING: University of Brasilia, Brazil
METHODS: Searches were conducted of the Cochrane Library, MEDLINE, CINAHL, PEDro, PsycINFO and EMBASE electronic databases for relevant articles published up to June 2018. No restrictions were imposed regarding the year of publication. The inclusion criteria were randomized controlled trials involving adults with SCI comparing ES to an active or passive control. Two independent reviewers extracted the data from the selected studies and methodological quality was assessed using the PEDro scale.
RESULTS: The initial search led to the retrieval of 164 studies, seven of which met the eligibility criteria, but only six were included in the meta-analysis. The six studies comprised 104 patients with complete or incomplete SCI. In the two studies that investigated the use of ES on muscle volume of the lower limbs, the overall effect was statistically significant in patients with acute SCI (mean difference: 0.86; 95% CI: 0.04 to 1.69; p < 0.04). Among the four studies that examined the use of ES for spasticity of the lower limb, the overall effect was non-significant (mean difference: 0.55; 95% CI: -0.31 to 1.41; p = 0.21).
CONCLUSIONS: Electrical stimulation was found to be an effective method for increasing muscle volume in SCI patients, but had no effect on spasticity. Further investigation of the effect of ES on spasticity in SCI is needed.

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Mesh:

Year:  2019        PMID: 30696926     DOI: 10.1038/s41393-019-0250-z

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  5 in total

Review 1.  Physiotherapy interventions for the treatment of spasticity in people with spinal cord injury: a systematic review.

Authors:  Paulo Henrique Ferreira de Araujo Barbosa; Joanne V Glinsky; Emerson Fachin-Martins; Lisa A Harvey
Journal:  Spinal Cord       Date:  2021-02-09       Impact factor: 2.772

2.  Epidural oscillating field stimulation increases axonal regenerative capacity and myelination after spinal cord trauma.

Authors:  Maria Bacova; Katarina Bimbova; Alexandra Kisucka; Nadezda Lukacova; Jan Galik
Journal:  Neural Regen Res       Date:  2022-12       Impact factor: 6.058

3.  Identification of four differentially expressed genes associated with acute and chronic spinal cord injury based on bioinformatics data.

Authors:  Su-Ping Niu; Ya-Jun Zhang; Na Han; Xiao-Feng Yin; Dian-Ying Zhang; Yu-Hui Kou
Journal:  Neural Regen Res       Date:  2021-05       Impact factor: 5.135

4.  Identification of hub genes in the subacute spinal cord injury in rats.

Authors:  Lei Yan; Jiawei Fu; Xiong Dong; Baishen Chen; Hongxiang Hong; Zhiming Cui
Journal:  BMC Neurosci       Date:  2022-08-27       Impact factor: 3.264

5.  Reduction in post-spinal cord injury spasticity by combination of peripheral nerve grafting and acidic fibroblast growth factor infusion in monkeys.

Authors:  Wei-Ming Sun; Chao-Lin Ma; Jiang Xu; Ji-Ping He
Journal:  J Int Med Res       Date:  2021-06       Impact factor: 1.671

  5 in total

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