| Literature DB >> 30695692 |
Nieves Peltzer1, Henning Walczak2.
Abstract
TAK1 is a key mediator of proinflammatory signals. In this issue of Developmental Cell, Naito et al. (2019) report that TAK1 loss from endothelial cells in adult mice results in intestinal and hepatic vascular destruction due to TNF-induced death of endothelial cells. Additionally, endothelial TAK1 deletion reduces tumor burden.Entities:
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Year: 2019 PMID： 30695692 DOI： 10.1016/j.devcel.2019.01.011
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270