Literature DB >> 30692493

[CA19-9 Producing Gastric Cancer with Early Recurrence of Multiple Colon Metastases Following Gastrectomy-A Case Report].

Yusuke Okubo1, Yasuhito Kawasaki, Takeshi Tono, Takaaki Ishii, Hisashi Hara, Shuho Senba, Seiji Yasuda, Minoru Otsuru.   

Abstract

A 90-year-old male underwent total gastrectomy for gastric cancer 10 months earlier. The cancer was pathologically diagnosed as Stage ⅢA. Preoperative serum CA19-9 level was as high as 1,326 U/mL, but quickly decreased after surgery. Although the serum CA19-9 level gradually re-increased, CT did not reveal recurrence of the disease. Ten months following surgery, the patient visited our hospital due to vomiting, and ileus was suspected because of finding of sigmoid colon tumors in the abdominalCT. Colonoscopy showed a circumferentialtumor with severe stenosis in the sigmoid colon, which was diagnosed as tubular adenocarcinoma by biopsy. After preoperative diagnosis of multiple colon cancers, sigmoidectomy was performed. A total of 4 tumors were revealed in the resected specimen. Pathological findings showed cancer cells with nuclear atypia in all tumors, which was very similar to findings in the previous gastric cancer. Immunohistochemical staining confirmed high expression of CA19-9 in both gastric and colon tumors. We concluded that the tumors were metastases of the CA19-9 producing gastric cancer.

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Year:  2018        PMID: 30692493

Source DB:  PubMed          Journal:  Gan To Kagaku Ryoho        ISSN: 0385-0684


  1 in total

1.  Nomogram-based prediction of survival in unresectable or metastatic gastric cancer patients with good performance status who received first-line chemotherapy.

Authors:  Jin Wang; Bowen Yang; Zhi Li; Jinglei Qu; Jing Liu; Na Song; Ying Chen; Yu Cheng; Simeng Zhang; Zhongqing Wang; Xiujuan Qu; Yunpeng Liu
Journal:  Ann Transl Med       Date:  2020-03
  1 in total

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