| Literature DB >> 30692463 |
Yoshiyuki Motoki1, Keishi Sugimoto, Hideki Sakisaka, Katsutoshi Nakano, Kazuomi Kan, Kazunori Nakaguchi, Sadayuki Doi.
Abstract
A 62-year-old man with diarrhea and metastases was found to harbor 2 rectal cancers. Both lateral lymph nodes were suspected based on CT and PET-CT(cT3N3M0, cStage Ⅲb). We planned to administer neoadjuvant chemotherapy(NAC) (CapeOX plus Bmab). After 4 courses of NAC, the sizes of both the primary tumor and lymph nodes decreased(partial response: PR). We performed laparoscopic abdominoperineal resection of the rectum(APR)with dissection of both lateral lymph nodes. The therapeutic effect was PR(few residual cancer cells)(Grade 2). After 4 courses of adjuvant chemotherapy (CapeOX), there have been no signs of recurrence for 8 months. This case suggests that laparoscopic APR after NAC with CapeOX plus Bmab for locally advanced rectal cancer is a potentially effective procedure.Entities:
Mesh:
Year: 2018 PMID: 30692463
Source DB: PubMed Journal: Gan To Kagaku Ryoho ISSN: 0385-0684