| Literature DB >> 30691720 |
Anne E Dixon1, Fernando Holguin2.
Abstract
Obesity is a major risk factor for asthma. This association appears related to altered dietary composition and metabolic factors that can directly affect airway reactivity and airway inflammation. This article discusses how specific changes in the western diet and metabolic changes associated with the obese state affect inflammation and airway reactivity and reviews evidence that interventions targeting weight, dietary components, lifestyle, and metabolism might improve outcomes in asthma.Entities:
Keywords: Airway reactivity; Asthma; Diet; Immunometabolism; Metabolic syndrome; Microbiome; Obesity
Mesh:
Year: 2018 PMID: 30691720 PMCID: PMC6355154 DOI: 10.1016/j.ccm.2018.10.007
Source DB: PubMed Journal: Clin Chest Med ISSN: 0272-5231 Impact factor: 2.878