| Literature DB >> 30690921 |
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Abstract
Entities:
Year: 2019 PMID: 30690921 PMCID: PMC6349147 DOI: 10.1111/jcmm.14142
Source DB: PubMed Journal: J Cell Mol Med ISSN: 1582-1838 Impact factor: 5.310
Figure 2IGF2 is the host gene of miR‐483‐3p. A, The mRNA and protein expression levels of IGF2 were lower in HSCR tissues than controls determined by qRT‐PCR and Western blot. B, The 293T and SH‐SY5Y cells were transfected with IGF2 siRNA and then the expression of miR‐483‐3p was reduced in both cell lines. C, Cotransfection of miR‐483‐3p mimics partially rescued the IGF2 siRNA‐mediated decrease in cell migration and proliferation. Absorbance at 450 nm was presented as mean ± SE. *means significant difference *P < 0.05, **P < 0.01, ***P < 0.0001