Literature DB >> 30690434

CMOS stimulating chips capable of wirelessly driving 473 electrodes for a cortical vision prosthesis.

Yan T Wong1, Timothy Feleppa, Anand Mohan, Damien Browne, Julian Szlawski, Jeffrey V Rosenfeld, Arthur Lowery.   

Abstract

OBJECTIVE: Implantable neural stimulating and recording devices have the potential to restore capabilities such as vision or motor control to disabled patients, improving quality of life. Implants with a large number of stimulating electrodes typically utilize implanted batteries and/or subcutaneous wiring to deal with their high-power consumption and high data throughput needed to address all electrodes with low latency. The use of batteries places severe limitations on the implant's size, usable duty cycle, device longevity while subcutaneous wiring increases the risk of infection and mechanical damage due to device movement. APPROACH: To overcome these limitations, we have designed and implemented a system that supports up to 473 implanted stimulating microelectrodes, all wirelessly powered and individually controlled by micropower application specific integrated circuits (ASICs). MAIN
RESULTS: Each ASIC controls 43 electrodes and draws 3.18 mW of power when stimulating through 24 channels. We measured the linearity of the digital-to-analog convertors (DACs) to be 0.21 LSB (integrated non-linearity) and the variability in timing of stimulation pulses across ASICs to be 172 ns. SIGNIFICANCE: This work demonstrates the feasibility of a new low power ASIC designed to be implanted in the visual cortex of humans. The fully implantable device will greatly reduce the risks of infection and damage due to mechanical issues.

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Year:  2019        PMID: 30690434     DOI: 10.1088/1741-2552/ab021b

Source DB:  PubMed          Journal:  J Neural Eng        ISSN: 1741-2552            Impact factor:   5.379


  3 in total

Review 1.  New Vision for Visual Prostheses.

Authors:  Alexander Farnum; Galit Pelled
Journal:  Front Neurosci       Date:  2020-02-18       Impact factor: 4.677

Review 2.  A narrative review of cortical visual prosthesis systems: the latest progress and significance of nanotechnology for the future.

Authors:  Xi Liu; Peipei Chen; Xuemeng Ding; Anning Liu; Peng Li; Cheng Sun; Huaijin Guan
Journal:  Ann Transl Med       Date:  2022-06

3.  Multichannel stimulation module as a tool for animal studies on cortical neural prostheses.

Authors:  Yuki Hayashida; Seiji Kameda; Yuichi Umehira; Shinnosuke Ishikawa; Tetsuya Yagi
Journal:  Front Med Technol       Date:  2022-09-13
  3 in total

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