Yidan Zhu1, Xin Yu, Yangfeng Wu, Chuan Shi, Aihua Zhang, Ronghuan Jiang, Shenshen Li, Guifang Guo, Runlin Gao, James A Blumenthal. 1. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina (Ms Zhu and Dr Blumenthal); Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China (Ms Zhu and Dr Wu); Peking University Institute of Mental Health (Sixth Hospital), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, China (Drs Yu and Shi); The George Institute for Global Health at Peking University Health Science Center, Beijing, China (Dr Wu and Mss Zhang and Li); Peking University Clinical Research Institute, Beijing, China (Dr Wu); Department of Psychological Medicine, Chinese PLA (People's Liberation Army) General Hospital, and Department of Psychological Medicine, Chinese PLA (People's Liberation Army) Medical School, Beijing, China (Dr Jiang); Peking University School of Nursing, Beijing, China (Dr Guo); and the Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Dr Gao).
Abstract
PURPOSE: This study sought to examine associations between depression and unhealthy lifestyle behaviors in Chinese patients with acute coronary syndromes (ACS). METHODS: This cross-sectional study included 4043 ACS patients from 16 hospitals across China who participated in the I-Care (Integrating Depression Care in Acute Coronary Syndromes Patients) trial. Patients were enrolled between November 2014 and January 2017. Depression was assessed with the Patient Health Questionnaire-9 (PHQ-9). Five lifestyle behaviors were assessed: smoking, drinking, body mass index (BMI), physical activity, and sleep quality. RESULTS: A total of 135 patients (3.3%) were considered clinically depressed (PHQ-9 ≥10). After adjusting for covariates, physical activity and sleep quality were inversely related to PHQ-9 scores. Adjusted logistic models showed that depressed patients were 1.7 times likely to be physically inactive (OR = 1.74; 95% CI, 1.15-2.64) and 4.6 times likely to have poor sleep quality (OR = 4.60; 95% CI, 3.07-6.88) compared with nondepressed patients. The association of depression with smoking, unhealthy drinking, and unhealthy BMI was not significant after adjustment for demographic characteristics. Higher depression scores were found to be associated with a greater number of unhealthy lifestyle behaviors (P for trend < .001). CONCLUSIONS: The association of depression and unhealthy lifestyles in post-ACS patients suggests that reducing depressive symptoms and improving healthy lifestyle behaviors could potentially improve clinical outcomes in this vulnerable patient population.
PURPOSE: This study sought to examine associations between depression and unhealthy lifestyle behaviors in Chinese patients with acute coronary syndromes (ACS). METHODS: This cross-sectional study included 4043 ACS patients from 16 hospitals across China who participated in the I-Care (Integrating Depression Care in Acute Coronary SyndromesPatients) trial. Patients were enrolled between November 2014 and January 2017. Depression was assessed with the Patient Health Questionnaire-9 (PHQ-9). Five lifestyle behaviors were assessed: smoking, drinking, body mass index (BMI), physical activity, and sleep quality. RESULTS: A total of 135 patients (3.3%) were considered clinically depressed (PHQ-9 ≥10). After adjusting for covariates, physical activity and sleep quality were inversely related to PHQ-9 scores. Adjusted logistic models showed that depressedpatients were 1.7 times likely to be physically inactive (OR = 1.74; 95% CI, 1.15-2.64) and 4.6 times likely to have poor sleep quality (OR = 4.60; 95% CI, 3.07-6.88) compared with nondepressed patients. The association of depression with smoking, unhealthy drinking, and unhealthy BMI was not significant after adjustment for demographic characteristics. Higher depression scores were found to be associated with a greater number of unhealthy lifestyle behaviors (P for trend < .001). CONCLUSIONS: The association of depression and unhealthy lifestyles in post-ACS patients suggests that reducing depressive symptoms and improving healthy lifestyle behaviors could potentially improve clinical outcomes in this vulnerable patient population.
Authors: Floriana S Luppino; Leonore M de Wit; Paul F Bouvy; Theo Stijnen; Pim Cuijpers; Brenda W J H Penninx; Frans G Zitman Journal: Arch Gen Psychiatry Date: 2010-03
Authors: Clara K Chow; Sanjit Jolly; Purnima Rao-Melacini; Keith A A Fox; Sonia S Anand; Salim Yusuf Journal: Circulation Date: 2010-02-01 Impact factor: 29.690
Authors: Katharine A Bradley; Anna F DeBenedetti; Robert J Volk; Emily C Williams; Danielle Frank; Daniel R Kivlahan Journal: Alcohol Clin Exp Res Date: 2007-04-19 Impact factor: 3.455
Authors: Mary A Whooley; Peter de Jonge; Eric Vittinghoff; Christian Otte; Rudolf Moos; Robert M Carney; Sadia Ali; Sunaina Dowray; Beeya Na; Mitchell D Feldman; Nelson B Schiller; Warren S Browner Journal: JAMA Date: 2008-11-26 Impact factor: 56.272
Authors: Heather S Lett; James A Blumenthal; Michael A Babyak; Andrew Sherwood; Timothy Strauman; Clive Robins; Mark F Newman Journal: Psychosom Med Date: 2004 May-Jun Impact factor: 4.312
Authors: Kay-Tee Khaw; Nicholas Wareham; Sheila Bingham; Ailsa Welch; Robert Luben; Nicholas Day Journal: PLoS Med Date: 2008-01-08 Impact factor: 11.069