Literature DB >> 30686808

Heart Transplantation Ameliorates Ambulation Capacity in Patients With Muscular Dystrophy - An Analysis of 9 Cases.

Osamu Seguchi1, Kensuke Kuroda1, Tomoyuki Fujita2, Yuto Kumai1, Seiko Nakajima1, Takuya Watanabe1, Masanobu Yanase1, Yorihiko Matsumoto2, Satsuki Fukushima2, Koichi Kimura3, Norihide Fukushima1.   

Abstract

BACKGROUND: Heart transplantation (HTx) is reported to have a comparable effect on the prognosis of heart failure patients without muscular disease and for those with muscular dystrophy (MD). However, little is known about the changes in muscular diseases in patients with MD after HTx. Methods and 
Results: We assessed the ambulatory capacity of 9 patients with MD who underwent HTx. All patients demonstrated improvement in ambulation to varying degrees and 1 patient successfully climbed Mount Fuji 3.8 years after HTx.
CONCLUSIONS: HTx potentially improves not only the prognosis but also the ambulatory capacity of patients with MD.

Entities:  

Keywords:  Advanced heart failure; Ambulation; Exercise capacity; Heart transplantation; Muscular dystrophy

Mesh:

Year:  2019        PMID: 30686808     DOI: 10.1253/circj.CJ-18-1060

Source DB:  PubMed          Journal:  Circ J        ISSN: 1346-9843            Impact factor:   2.993


  2 in total

1.  Early cardiac rehabilitation after heart transplantation in a patient with limb-girdle muscular dystrophy: A case report.

Authors:  Youngmo Kim; Min Kyung Park; Myung-Jun Shin; Yong Beom Shin; Hye Won Lee; Ra Yu Yun; Byeong-Ju Lee
Journal:  Medicine (Baltimore)       Date:  2022-07-29       Impact factor: 1.817

2.  A medium-chain triglyceride containing ketogenic diet exacerbates cardiomyopathy in a CRISPR/Cas9 gene-edited rat model with Duchenne muscular dystrophy.

Authors:  Yuri Fujikura; Koichi Kimura; Keitaro Yamanouchi; Hidetoshi Sugihara; Masaki Hatakeyama; Haotong Zhuang; Tomoki Abe; Masao Daimon; Hiroyuki Morita; Issei Komuro; Katsutaka Oishi
Journal:  Sci Rep       Date:  2022-07-08       Impact factor: 4.996

  2 in total

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