Literature DB >> 30686696

The association of patient and burn characteristics with itching and pain severity.

Atulya Prasad1, Henry C Thode1, Steven Sandoval2, Adam J Singer3.   

Abstract

INTRODUCTION: Itch after burn injury causes significant distress to patients and can hamper functional recovery. Itching can persist on a time scale ranging from several weeks to even years after injury. In this study, we sought to determine predictors of itching after burn injury.
METHODS: We compared itch and pain severity among patients included in a burn registry at a level 1 trauma center. Both itch and pain severity was based on a 5-point scale. ANOVA, chi-squared, and multivariate analyses were performed to determine predictors of itch and pain severity.
RESULTS: Of the 1159 patients enrolled in the registry, 58% were male and 42% female, with a median age (IQR) of 27 (8-47) years. Most patients were diagnosed with 2nd degree superficial (41%) or deep (43%) burns. Upper extremities were the most common location of burn injury (59%), followed by lower extremities (31%), trunk (22%), and face/neck (20%). More than half (53%) of enrolled patients reported itching, ranging from minimal (19%) to severe (7%) itching. Multivariate analyses revealed age, sex (female), extent of burn injuries, and location (face/neck) to be predictors of itch after burn. Predictors of pain after burn were slightly different: age, extent of burn, and depth of burn.
CONCLUSION: Pain and itch after burn injuries are predicted by slightly different variables, presumably secondary to different underlying mechanisms. We conclude that age, sex (female), extent of burn injuries (total body surface area %), and injuries to the face/neck predict itching of greater severity. Patients with burn injuries that match these parameters would require greater care and closer follow up to reduce itching after healing.
Copyright © 2018 Elsevier Ltd and ISBI. All rights reserved.

Entities:  

Keywords:  Burn management; Burns; Itch management; Pain; Pruritus

Mesh:

Year:  2019        PMID: 30686696     DOI: 10.1016/j.burns.2018.06.011

Source DB:  PubMed          Journal:  Burns        ISSN: 0305-4179            Impact factor:   2.744


  2 in total

1.  Validation of PROMIS-29 domain scores among adult burn survivors: A National Institute on Disability, Independent Living, and Rehabilitation Research Burn Model System Study.

Authors:  Kara McMullen; Alyssa Bamer; Colleen M Ryan; Jeffrey C Schneider; Nicole Gibran; Barclay T Stewart; Tracy Mroz; Steven Wolf; Dagmar Amtmann
Journal:  J Trauma Acute Care Surg       Date:  2022-01-01       Impact factor: 3.697

2.  The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.

Authors:  Junji Xu; Peter Zanvit; Lei Hu; Pang-Yen Tseng; Na Liu; Fu Wang; Ousheng Liu; Dunfang Zhang; Wenwen Jin; Nancy Guo; Yichen Han; Jessica Yin; Alexander Cain; Mark A Hoon; Songlin Wang; WanJun Chen
Journal:  Immunity       Date:  2020-07-15       Impact factor: 31.745

  2 in total

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