Jose Alejandro Lugo-Baruqui1, Rajinikanth Ayyathurai2, Adavan Sriram3, Kothai Divya Pragatheeshwar4. 1. Hospital Civil de Guadalajara "Fray Antonio Alcalde", Division of Transplant, Department of Surgery, University of Guadalajara, Guadalajara, Mexico. alejandro.lugo.b@gmail.com. 2. Division of Urology, Northeast Georgia Medical Center, Gainesville, Georgia. uroayya@gmail.com. 3. Division of Urology, Northeast Georgia Medical Center, Gainesville, Georgia. 4. Department of Nephrology, University of Oklahoma, Tulsa, OK, USA.
Abstract
PURPOSE OF REVIEW: Few procedures involve the ischemia-reperfusion injury to organs purposely. Two clear examples in urologic surgery consist on kidney transplantation and partial nephrectomies. RECENT FINDINGS: Mannitol is an osmotic diuretic that is commonly used in partial nephrectomies and kidney transplantation to increase renal blood flow and decrease warm-ischemia-related renal injury to preserve estimated glomerular filtration rate (eGFR). We review the current evidence for the use of mannitol and its effects on these procedures.
PURPOSE OF REVIEW: Few procedures involve the ischemia-reperfusion injury to organs purposely. Two clear examples in urologic surgery consist on kidney transplantation and partial nephrectomies. RECENT FINDINGS:Mannitol is an osmotic diuretic that is commonly used in partial nephrectomies and kidney transplantation to increase renal blood flow and decrease warm-ischemia-related renal injury to preserve estimated glomerular filtration rate (eGFR). We review the current evidence for the use of mannitol and its effects on these procedures.
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