Zhiyi Li1, Tao Xu2, Zhaoai Li3, Jian Gong4, Qing Liu5, Lan Zhu6. 1. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, No. 1 ShuaiFu Road, Dongcheng District, Beijing, People's Republic of China. 2. Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing, People's Republic of China. 3. Department of Gynecology and Obstetrics, Children's Hospital of Shanxi Province, Shanxi, People's Republic of China. 4. Department of Gynecology and Obstetrics, Maternal and Child Health Hospital of Wuxi, Jiangsu, People's Republic of China. 5. Department of Gynecology and Obstetrics, Maternal and Child Health Hospital of Gansu Province, Lanzhou, People's Republic of China. 6. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, No. 1 ShuaiFu Road, Dongcheng District, Beijing, People's Republic of China. zhu_julie@vip.sina.com.
Abstract
INTRODUCTION AND HYPOTHESIS: We aimed to investigate the prevalence and risk factors of symptomatic pelvic organ prolapse (POP) in rural China. METHODS: A cross-sectional study of POP was conducted in rural China from February 2014 to March 2016. In total, 25,864 rural women were recruited. All were asked to complete a questionnaire that included questions about their age, job, parity, diseases, and so on. Symptomatic POP was assessed using Pelvic Organ Prolapse Quantification (POP-Q) system staging and validation questionnaires. Multivariate logistic regression was used to assess the factors associated with symptomatic POP. RESULTS: The prevalence of symptomatic POP was 9.10%. There was a consistent trend toward an increasing prevalence of POP with increasing age, ranging from 2.53 to 13.40% (P < 0.0001). Women aged 50-59 years [adjusted odds ratio (AOR) 1.86, 95% confidence interval (CI) 1.46-2.37] were more likely to have POP than women aged 20-29 years. POP was positively associated with giving birth to more than three children (AOR 2.18, 95% CI 1.88-2.43). Cesarean section was a significant protective factor (AOR = 0.34, 95% CI 0.33-0.49) compared with vaginal delivery. Multivariate logistic regression analysis showed that obesity, constipation, smoking, coughing, gynecological diseases, and other physical diseases were also associated with POP. CONCLUSIONS: Symptomatic POP affects a substantial proportion of women in rural China. Older age, multiparity, vaginal delivery, obesity, and many chronic conditions significantly increased the odds of developing symptomatic POP. Additional healthcare campaigns are needed to educate women in rural areas about POP.
INTRODUCTION AND HYPOTHESIS: We aimed to investigate the prevalence and risk factors of symptomatic pelvic organ prolapse (POP) in rural China. METHODS: A cross-sectional study of POP was conducted in rural China from February 2014 to March 2016. In total, 25,864 rural women were recruited. All were asked to complete a questionnaire that included questions about their age, job, parity, diseases, and so on. Symptomatic POP was assessed using Pelvic Organ Prolapse Quantification (POP-Q) system staging and validation questionnaires. Multivariate logistic regression was used to assess the factors associated with symptomatic POP. RESULTS: The prevalence of symptomatic POP was 9.10%. There was a consistent trend toward an increasing prevalence of POP with increasing age, ranging from 2.53 to 13.40% (P < 0.0001). Women aged 50-59 years [adjusted odds ratio (AOR) 1.86, 95% confidence interval (CI) 1.46-2.37] were more likely to have POP than women aged 20-29 years. POP was positively associated with giving birth to more than three children (AOR 2.18, 95% CI 1.88-2.43). Cesarean section was a significant protective factor (AOR = 0.34, 95% CI 0.33-0.49) compared with vaginal delivery. Multivariate logistic regression analysis showed that obesity, constipation, smoking, coughing, gynecological diseases, and other physical diseases were also associated with POP. CONCLUSIONS: Symptomatic POP affects a substantial proportion of women in rural China. Older age, multiparity, vaginal delivery, obesity, and many chronic conditions significantly increased the odds of developing symptomatic POP. Additional healthcare campaigns are needed to educate women in rural areas about POP.
Entities:
Keywords:
Epidemiology; Pelvic organ prolapse; Prevalence; Risk factors; Rural
Authors: Luiz Gustavo Oliveira Brito; Glaucia Miranda Varella Pereira; Pamela Moalli; Oksana Shynlova; Jittima Manonai; Adi Yehuda Weintraub; Jan Deprest; Maria Augusta T Bortolini Journal: Int Urogynecol J Date: 2021-08-05 Impact factor: 1.932