Literature DB >> 30684744

Community acquired Stenotrophomonas maltophilia discitis: Diagnosis aided by shotgun metagenomic sequencing.

Gang Wang1, Nannan Xu2, Lulu Yang2, Feng Zheng2, Lintao Sai2, Jiale Zhou3, Shangxin Yang4.   

Abstract

We report a rare case of culture negative L4-L5 discitis and epidural abscess in an immunocompetent child who had dry cupping therapy performed to treat low back strain. The causative pathogen was identified as Stenotrophomonas maltophilia by shotgun metagenomic sequencing of spinal cord aspirate after more than one month of unsuccessful empirical treatment with 6 different antibiotics. The patient was successfully treated with Sulfamethoxazole-trimethoprim and minocycline. Cupping therapy is a very popular medical procedure widely used in China, but the potential risk for severe infections such as discitis and epidural abscess described in this case should be recognized.
Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Discitis; Dry cupping therapy; Epidural abscess; Shotgun metagenomic sequencing; Stenotrophomonas maltophilia

Mesh:

Substances:

Year:  2019        PMID: 30684744     DOI: 10.1016/j.ijid.2019.01.032

Source DB:  PubMed          Journal:  Int J Infect Dis        ISSN: 1201-9712            Impact factor:   3.623


  5 in total

Review 1.  Clinical challenges treating Stenotrophomonas maltophilia infections: an update.

Authors:  Maria F Mojica; Romney Humphries; John J Lipuma; Amy J Mathers; Gauri G Rao; Samuel A Shelburne; Derrick E Fouts; David Van Duin; Robert A Bonomo
Journal:  JAC Antimicrob Resist       Date:  2022-05-05

Review 2.  Characteristics, Management and Outcomes of Spondylodiscitis in Children: A Systematic Review.

Authors:  Irene Ferri; Gabriele Ristori; Catiuscia Lisi; Luisa Galli; Elena Chiappini
Journal:  Antibiotics (Basel)       Date:  2020-12-31

3.  Evolution of cefiderocol resistance in Stenotrophomonas maltophilia using in vitro serial passage techniques.

Authors:  Brian J Werth; Nathaniel K Ashford; Kelsi Penewit; Adam Waalkes; Elizabeth A Holmes; Andrew Bryan; Stephen J Salipante
Journal:  JAC Antimicrob Resist       Date:  2022-02-08

4.  Community-Acquired Stenotrophomonas Maltophilia Infection in a Child: A Case Report and Literature Review.

Authors:  ZhiHong Jiang; YiFan Ren; ChuanXin Zhang; Yu Yin; ChaoHui Li
Journal:  Infect Drug Resist       Date:  2022-09-19       Impact factor: 4.177

5.  Advances in the Microbiology of Stenotrophomonas maltophilia.

Authors:  Joanna S Brooke
Journal:  Clin Microbiol Rev       Date:  2021-05-26       Impact factor: 50.129

  5 in total

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