Literature DB >> 30677472

Models of attention-deficit hyperactivity disorder.

Peter R Killeen1.   

Abstract

One of the most notable aspects of the behavior of individuals with Attention Deficit Hyperactivity Disorder (ADHD) is increased variability in many aspects of their behavior, including response times and attentional focus. Among the many theories of ADHD is one that identifies its material cause as phasic malnutrition of the neurons required to maintain constancy of performance. Of the diverse predictions issuing from this theory, one concerns ubiquitous data: response times and their variance in decision tasks. This paper reviews that behavioral neuroenergetics theory and model, shows how they predict representative data, and suggests their relevance to researchers studying animal models of ADHD.
Copyright © 2019 Elsevier B.V. All rights reserved.

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Keywords:  ADHD; Astrocyte-neuron lactate shuttle; Attention deficit hyperactivity disorder; Diffusion-decision models; Lactate; Neuroenergetics

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Year:  2019        PMID: 30677472     DOI: 10.1016/j.beproc.2019.01.001

Source DB:  PubMed          Journal:  Behav Processes        ISSN: 0376-6357            Impact factor:   1.777


  1 in total

1.  SHR/NCrl rats as a model of ADHD can be discriminated from controls based on their brain, blood, or urine metabolomes.

Authors:  Patrick Emond; Laurent Galineau; Camille Dupuy; Pierre Castelnau; Sylvie Mavel; Antoine Lefevre; Lydie Nadal-Desbarats; Sylvie Bodard; Julie Busson; Diane Dufour-Rainfray; Helene Blasco
Journal:  Transl Psychiatry       Date:  2021-04-22       Impact factor: 6.222

  1 in total

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