Literature DB >> 3067665

[Antimicrobial activity of polyhydroxynaphthoquinones from sea urchins].

S I Stekhova, E B Shentsova, E B Kol'tsova, N I Kulesh.   

Abstract

Antimicrobial activity of polyhydroxynaphthoquinones from sea urchins was studied. 6-Ethyl-2,3,5,7,8-pentahydroxy-1,4-naphthoquinone (equinochrome A) containing the beta-ethyl functional group was found to be the most active substance. Methylation of beta-hydroxyls markedly increased the inhibitory effect of the derivatives as compared to that of the initial quinones.

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Year:  1988        PMID： 3067665

Source DB:  PubMed          Journal:  Antibiot Khimioter        ISSN： 0235-2990


  4 in total

Review 1.  Naphthoquinones of the spinochrome class: occurrence, isolation, biosynthesis and biomedical applications.

Authors:  Yakun Hou; Elena A Vasileva; Alan Carne; Michelle McConnell; Alaa El-Din A Bekhit; Natalia P Mishchenko
Journal:  RSC Adv       Date:  2018-09-21       Impact factor: 4.036

2.  The Roles of Spinochromes in Four Shallow Water Tropical Sea Urchins and Their Potential as Bioactive Pharmacological Agents.

Authors:  Lola Brasseur; Elise Hennebert; Laurence Fievez; Guillaume Caulier; Fabrice Bureau; Lionel Tafforeau; Patrick Flammang; Pascal Gerbaux; Igor Eeckhaut
Journal:  Mar Drugs       Date:  2017-06-16       Impact factor: 5.118

3.  Echinometra mathaei and its ectocommensal shrimps: the role of sea urchin spinochrome pigments in the symbiotic association.

Authors:  Lola Brasseur; Guillaume Caulier; Gilles Lepoint; Pascal Gerbaux; Igor Eeckhaut
Journal:  Sci Rep       Date:  2018-12-03       Impact factor: 4.379

4.  Identification and quantification of spinochromes in body compartments of Echinometra mathaei's coloured types.

Authors:  Lola Brasseur; Marie Demeyer; Corentin Decroo; Guillaume Caulier; Patrick Flammang; Pascal Gerbaux; Igor Eeckhaut
Journal:  R Soc Open Sci       Date:  2018-08-22       Impact factor: 2.963
  4 in total

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