| Literature DB >> 30676240 |
Isadora Rodrigues da Silva1, Caio Augusto Martins Aires1,2, Orlando Carlos Conceição-Neto1, Ivson Cassiano de Oliveira Santos1, Natacha Ferreira Pereira1, José Procópio Moreno Senna3, Ana Paula D'Alincourt Carvalho-Assef1, Marise Dutra Asensi1, Cláudio Marcos Rocha-de-Souza1.
Abstract
New Delhi metallo-β-lactamase (NDM)-producing bacteria have been identified at a worrying rate in Brazil since 2013. Owing to the need to understand the extent of their spread, this study reports the dissemination of blaNDM in different species of Gram-negative bacilli in different regions and states of Brazil. A total of 81 isolates from nine states were studied, including 11 species. All isolates carried blaNDM-1 variant and were considered multidrug resistant. Colistin and amikacin were the agents with higher activity compared with the other drugs tested. The findings indicate that the NDM-1 enzyme is already widespread in the country.Entities:
Keywords: Gram-negative bacilli; New Delhi metallo-β-lactamase; dissemination
Mesh：
Substances：
Year: 2019 PMID： 30676240 DOI： 10.1089/mdr.2018.0240
Source DB: PubMed Journal: Microb Drug Resist ISSN： 1076-6294 Impact factor: 3.431