Literature DB >> 30676067

α-Tetralone glycosides from the green walnut husks of Juglans mandshurica Maxim. and their cytotoxic activities.

Yuan-Yuan Zhou1, Shuang Guo1, Ying Wang1, Hong-Juan Song1, Hui-Rui Gao1, Xiao-Juan Zhang2, Yan-Ping Sun1, Yan Liu1, Bing-You Yang1, Hai-Xue Kuang1.   

Abstract

Five new α-tetralone glycosides, juglanbiosides A-E (1-5), together with an α-tetralone derivative (15) and nine known 1,4-naphthoquinones (6-14) were isolated from the 95% EtOH extract of green walnut husks of Juglans mandshurica Maxim. Their structures were elucidated by comprehensive spectroscopic methods (1H, 13C NMR, DEPT, HSQC, HMBC, CD, HR-ESI-MS). In vitro cytotoxicities of all the isolated compounds were evaluated against BGC-823, HCT-15 and K562 cancer cell lines.[Formula: see text].

Entities:  

Keywords:  1,4-naphthoquinones; The green walnut husks Juglans mandshurica Maxim.; cytotoxic activities; α-tetralone glycosides

Year:  2019        PMID: 30676067     DOI: 10.1080/14786419.2018.1561681

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  3 in total

Review 1.  Juglans mandshurica Maxim.: A Review of Its Traditional Usages, Phytochemical Constituents, and Pharmacological Properties.

Authors:  Fei Luan; Ziyan Wang; Yan Yang; Yafei Ji; Haizhen Lv; Keqing Han; Daoheng Liu; Xiaofei Shang; Xirui He; Nan Zeng
Journal:  Front Pharmacol       Date:  2021-01-21       Impact factor: 5.810

2.  Green walnut husk extracts Proliferation and Migration in Gastric Cancer.

Authors:  Jiarong Zhang; Jinli Zhang; Chunbo Zhao; Hong Sui; Chun Feng Li; Lili Zhong; Qingxin Zhou; Yuxian Bai; Shijia An; Xiaoxue Du; Xiaoli Wei; Lei Liu
Journal:  J Cancer       Date:  2022-01-09       Impact factor: 4.207

3.  Ultrasonic-Assisted Extraction of Flavonoids from Juglans mandshurica Maxim.: Artificial Intelligence-Based Optimization, Kinetics Estimation, and Antioxidant Potential.

Authors:  Guodong Chu; Rui Liang; Chenmeng Wan; Jing Yang; Jing Li; Ruinan Wang; Linna Du; Ruixin Lin
Journal:  Molecules       Date:  2022-07-28       Impact factor: 4.927

  3 in total

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