| Literature DB >> 30676065 |
Quach Thi Thanh Van1,2, Le Thi Vien1, Tran Thi Hong Hanh1, Phan Thi Thanh Huong1, Nguyen The Cuong3, Nguyen Phuong Thao1, Nguyen Huy Thuan4, Nguyen Hai Dang1, Nguyen Van Thanh1, Nguyen Xuan Cuong1,2, Nguyen Hoai Nam1, Phan Van Kiem1, Chau Van Minh1.
Abstract
Using various chromatographic separations, three new acylated flavonoid glycosides, namely barringosides G-I (1-3), were isolated from the water-soluble extract of Barringtonia racemosa branches and leaves. The structure elucidation was performed by extensive analysis of the 1D and 2D NMR and HR-QTOF-MS data. Of the isolated compounds, barringoside I (3) showed moderate inhibitory effects on LPS-induced NO production in RAW264.7 cells with an IC50 of 52.48 ± 1.04 µM.Entities:
Keywords: Barringtonia racemosa; Lecythidaceae; NO production; flavonoid glycoside
Year: 2019 PMID： 30676065 DOI： 10.1080/14786419.2018.1560290
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861