Literature DB >> 30675504

Auxiliary Liver Transplantation as a Transient Treatment for Acute Liver Failure: Two Cases.

David N Perdigoto1, Luís Tomé1,2, Dulce Diogo2, José Ferrão2, Ricardo Martins2, Pedro Oliveira2, Guilherme Tralhão2,3, Emanuel Furtado2.   

Abstract

INTRODUCTION: Acute liver failure is an uncommon condition associated with a high mortality. Most patients do not survive without liver transplantation. In the last decades, auxiliary liver transplantation has emerged as a therapeutic option. CLINICAL CASE: The authors present two cases of acute liver failure that required liver transplantation. Given the patients' young age and the preserved macroscopic liver pattern evaluated in surgery, auxiliary liver transplantation was executed using different surgical approaches. Afterwards, following confirmed full native liver regeneration, the patients were submitted to auxiliary liver hepatectomy, which was accomplished without complications.
CONCLUSION: Auxiliary liver transplantation can be regarded as an effective temporary treatment for acute liver failure in selected cases, allowing an immunosuppression-free life.

Entities:  

Keywords:  Acute liver failure; Auxiliary liver transplantation; Immunosuppression; Liver transplantation

Year:  2018        PMID: 30675504      PMCID: PMC6341369          DOI: 10.1159/000487155

Source DB:  PubMed          Journal:  GE Port J Gastroenterol        ISSN: 2387-1954


  14 in total

1.  A novel technique for auxiliary partial liver transplantation with reno-portal anastomosis and avoidance of the hepatoduodenal ligament.

Authors:  J Ringers; A G Baranski; J Dubbeld; E Sarton; R A Veenendaal; A F M Schaapherder; E van der Linden; O T Terpstra; B van Hoek
Journal:  Am J Transplant       Date:  2006-11       Impact factor: 8.086

2.  Reuse of auxiliary liver grafts in second recipients with chronic liver disease.

Authors:  J Ringers; J Dubbeld; A G Baranski; M Coenraad; E Sarton; A F M Schaapherder; B van Hoek
Journal:  Am J Transplant       Date:  2007-11       Impact factor: 8.086

3.  Lessons from look-back in acute liver failure? A single centre experience of 3300 patients.

Authors:  William Bernal; Anna Hyyrylainen; Amit Gera; Vinod K Audimoolam; Mark J W McPhail; Georg Auzinger; Mohammed Rela; Nigel Heaton; John G O'Grady; Julia Wendon; Roger Williams
Journal:  J Hepatol       Date:  2013-02-22       Impact factor: 25.083

4.  Complete spontaneous liver graft disappearance after auxiliary liver transplantation.

Authors:  Safi Dokmak; Béatrice Aussilhou; François Durand; Valérie Paradis; Jacques Belghiti
Journal:  Hepatology       Date:  2014-07-28       Impact factor: 17.425

5.  Auxiliary versus orthotopic liver transplantation for acute liver failure. EURALT Study Group. European Auxiliary Liver Transplant Registry.

Authors:  B van Hoek; J de Boer; K Boudjema; R Williams; O Corsmit; O T Terpstra
Journal:  J Hepatol       Date:  1999-04       Impact factor: 25.083

6.  Centrilobular necrosis in autoimmune hepatitis: a histological feature associated with acute clinical presentation.

Authors:  H Hofer; C Oesterreicher; F Wrba; P Ferenci; E Penner
Journal:  J Clin Pathol       Date:  2006-03       Impact factor: 3.411

7.  Anti-mitochondrial M2 antibody-positive autoimmune hepatitis.

Authors:  Minoru Tomizawa; Fuminobu Shinozaki; Kazunori Fugo; Yasufumi Motoyoshi; Takao Sugiyama; Shigenori Yamamoto; Takashi Kishimoto; Naoki Ishige
Journal:  Exp Ther Med       Date:  2015-08-20       Impact factor: 2.447

8.  Auxiliary transplantation for acute liver failure: Histopathological study of native liver regeneration.

Authors:  Alberto Quaglia; Bernard C Portmann; A S Knisely; Alex S Knisely; Parthi Srinivasan; Paolo Muiesan; Julia Wendon; Michael A Heneghan; John G O'Grady; Marianne Samyn; Dino Hadzic; Anil Dhawan; Giorgina Mieli-Vergani; Nigel Heaton; Mohamed Rela
Journal:  Liver Transpl       Date:  2008-10       Impact factor: 5.799

9.  Auxiliary liver transplantation for acute liver failure.

Authors:  J Belghiti; D Sommacale; F Dondéro; F Zinzindohoué; A Sauvanet; F Durand
Journal:  HPB (Oxford)       Date:  2004       Impact factor: 3.647

10.  Clinical features of Japanese type 1 autoimmune hepatitis patients with zone III necrosis.

Authors:  Yasuhiro Miyake; Yoshiaki Iwasaki; Ryo Terada; Toru Onishi; Ryoichi Okamoto; Kouichi Takaguchi; Hiroshi Ikeda; Yasuhiro Makino; Haruhiko Kobashi; Kohsaku Sakaguchi; Yasushi Shiratori
Journal:  Hepatol Res       Date:  2007-06-07       Impact factor: 4.288

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