Literature DB >> 30674490

Radiation induced valvular disease: the internist's prospective.

Sundeep Kumar1,2, Hiren Patel1, Joyce Paulson1, Bernard Gros1.   

Abstract

Radiation-induced cardiac injury entails a wide spectrum of cardiovascular complications such as cardiomyopathy and valvular diseases among others. We present the internist's perspective and the challenges faced in managing these patients. There are guidelines addressing radiation-induced valvular disease (RIVD) including screening and treatment, but are often unrecognised by most internist's practice. A thorough cardiovascular examination and screening echocardiography may detect RIVD at an earlier stage. Early screening with transthoracic echocardiogram should be considered in asymptomatic or low-risk patients and more frequently in symptomatic and high-risk patients. The internists should educate their patients with prior chest irradiation, regarding the possible radiation related adverse cardiovascular effects and recommended screening. Lifestyle changes and aggressive cardiovascular risk modification should be emphasised, as concomitant hypertension, coronary artery disease and cardiomyopathy can have unfavourable effects in these patients. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  radiology; radiotherapy; unwanted effects / adverse reactions; valvar diseases

Mesh:

Substances:

Year:  2019        PMID: 30674490      PMCID: PMC6347939          DOI: 10.1136/bcr-2018-226989

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

1.  Effective dose reduction to cardiac structures using protons compared with 3DCRT and IMRT in mediastinal Hodgkin lymphoma.

Authors:  Bradford S Hoppe; Stella Flampouri; Zhong Su; Naeem Latif; Nam H Dang; James Lynch; Michael Joyce; Eric Sandler; Zuofeng Li; Nancy P Mendenhall
Journal:  Int J Radiat Oncol Biol Phys       Date:  2012-03-02       Impact factor: 7.038

2.  Cardiac surgery after mediastinal radiation: extent of exposure influences outcome.

Authors:  Albert S Y Chang; Nicholas G Smedira; Catherine L Chang; Monica M Benavides; Ulf Myhre; Jingyuan Feng; Eugene H Blackstone; Bruce W Lytle
Journal:  J Thorac Cardiovasc Surg       Date:  2007-01-08       Impact factor: 5.209

3.  Expert consensus for multi-modality imaging evaluation of cardiovascular complications of radiotherapy in adults: a report from the European Association of Cardiovascular Imaging and the American Society of Echocardiography.

Authors:  Patrizio Lancellotti; Vuyisile T Nkomo; Luigi P Badano; Jutta Bergler-Klein; Jutta Bergler; Jan Bogaert; Laurent Davin; Bernard Cosyns; Philippe Coucke; Raluca Dulgheru; Thor Edvardsen; Oliver Gaemperli; Maurizio Galderisi; Brian Griffin; Paul A Heidenreich; Koen Nieman; Juan C Plana; Steven C Port; Marielle Scherrer-Crosbie; Ronald G Schwartz; Igal A Sebag; Jens-Uwe Voigt; Samuel Wann; Phillip C Yang
Journal:  J Am Soc Echocardiogr       Date:  2013-09       Impact factor: 5.251

4.  Radiation induces osteogenesis in human aortic valve interstitial cells.

Authors:  Nicole A Nadlonek; Michael J Weyant; Jessica A Yu; Joseph C Cleveland; T Brett Reece; Xianzhong Meng; David A Fullerton
Journal:  J Thorac Cardiovasc Surg       Date:  2012-09-29       Impact factor: 5.209

  4 in total

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