Literature DB >> 30674260

Biological Activities of Artemisinin Derivatives Beyond Malaria.

Xiaoyan Liu1,2, Jianguo Cao2, Guozheng Huang2,3, Qingjie Zhao1, Jingshan Shen1.   

Abstract

Artemisinin is isolated from Artemisia annua L. with peroxide-containing sesquiterpene lactone structure. Because of its unique structural characteristics and promising anticancer, antivirus activities, it has recently received increasing attention. The aim of this review is to summarize recent discoveries of artemisinin's novel derivatives with new pharmaceutical effects beyond malaria with a focus on its antitumor and antivirus activity, as well as potential results of combination therapy with other clinical drugs. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Anticancer activity; Antiviral activity; Artemisinin; Artemisinin derivatives; Dimer; Trimer.

Mesh：

Substances：

Year:  2019        PMID： 30674260     DOI： 10.2174/1568026619666190122144217

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  9 in total

1.  Trichomonas vaginalis NTPDase inhibited by lycorine modulates the parasite-neutrophil interaction.

Authors:  Brenda Petró-Silveira; Graziela Vargas Rigo; Danielle da Silva Trentin; Alexandre José Macedo; Elisa Sauer; Elen de Oliveira Alves; Luciana Ruschel Tallini; Solange Cristina Garcia; Warley de Souza Borges; José Ângelo Silveira Zuanazzi; Tiana Tasca
Journal:  Parasitol Res       Date:  2020-06-11       Impact factor: 2.289

2.  Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii.

Authors:  Alex Rosenberg; Madeline R Luth; Elizabeth A Winzeler; Michael Behnke; L David Sibley
Journal:  Proc Natl Acad Sci U S A       Date:  2019-12-05       Impact factor: 11.205

Review 3.  Artemisia Extracts and Artemisinin-Based Antimalarials for COVID-19 Management: Could These Be Effective Antivirals for COVID-19 Treatment?

Authors:  Pawan K Agrawal; Chandan Agrawal; Gerald Blunden
Journal:  Molecules       Date:  2022-06-14       Impact factor: 4.927

4.  Zinc and Iron Homeostasis: Target-Based Drug Screening as New Route for Antifungal Drug Development.

Authors:  Claudia Simm; Robin C May
Journal:  Front Cell Infect Microbiol       Date:  2019-05-29       Impact factor: 5.293

5.  Hyaluronic acid functionalized ZnO nanoparticles co-deliver AS and GOD for synergistic cancer starvation and oxidative damage.

Authors:  Zhenkun Ren; Xibin Han; Lixin Wang; Yi Wang
Journal:  Sci Rep       Date:  2022-03-17       Impact factor: 4.379

6.  Network pharmacology-based predictions of active components and pharmacological mechanisms of Artemisia annua L. for the treatment of the novel Corona virus disease 2019 (COVID-19).

Authors:  Yexiao Tang; Xiaobo Li; Yueming Yuan; Hongying Zhang; Yuanyuan Zou; Zhiyong Xu; Qin Xu; Jianping Song; Changsheng Deng; Qi Wang
Journal:  BMC Complement Med Ther       Date:  2022-03-03

7.  In Vitro Activity of the Arylaminoartemisinin GC012 against Helicobacter pylori and Its Effects on Biofilm.

Authors:  Francesca Sisto; Simone Carradori; Sarah D'Alessandro; Nadia Santo; Norma Lattuada; Richard K Haynes; Donatella Taramelli; Rossella Grande
Journal:  Pathogens       Date:  2022-06-29

8.  Sesquiterpenes from Artemisia annua and Their Cytotoxic Activities.

Authors:  Xiao Han; Yao Chai; Cheng Lv; Qianqian Chen; Jinling Liu; Yongli Wang; Guixin Chou
Journal:  Molecules       Date:  2022-08-10       Impact factor: 4.927

9.  Ethanolic extract of Artemisia campestris subsp. glutinosa (Besser) Batt. inhibits HIV-1 replication in vitro through the activity of terpenes and flavonoids on viral entry and NF-κB pathway.

Authors:  L Apaza Ticona; P Bermejo; J A Guerra; M J Abad; M Beltrán; R Martín Lázaro; J Alcamí; L M Bedoya
Journal:  J Ethnopharmacol       Date:  2020-08-03       Impact factor: 4.360
  9 in total

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