Literature DB >> 30674042

Automated Generation of CONSORT Diagrams Using Relational Database Software.

Teresa O'Leary1,2, June Weiss1,2, Benjamin Toll3, Cynthia Brandt1,2,4, Steven L Bernstein1,2,5.   

Abstract

BACKGROUND: Investigators conducting prospective clinical trials must report patient flow using the Consolidated Standards of Reporting Trials (CONSORT) statement. Depending on how data are collected, this can be a laborious, time-intensive process. However, because many trials enter data electronically, CONSORT diagrams may be generated in an automated fashion.
OBJECTIVE: Our objective was to use an off-the-shelf software to develop a technique to generate CONSORT diagrams automatically.
METHODS: During a recent trial, data were entered into FileMaker Pro, a commercially available software, at enrollment and three waves of follow-up. Patient-level data were coded to automatically generate CONSORT diagrams for use by the study team.
RESULTS: From August 2012 to July 2014, 1,044 participants were enrolled. CONSORT diagrams were generated weekly for study team meetings to track follow-ups at 1, 6, and 12 months, for 960 (92%), 921 (90%), and 871 (88%) participants who were contacted or deceased, respectively. Reasons for loss to follow-up were captured at each follow-up.
CONCLUSION: CONSORT diagrams can be generated using a standard software for any trial and can facilitate data collection, project management, and reporting. Georg Thieme Verlag KG Stuttgart · New York.

Entities:  

Year:  2019        PMID: 30674042      PMCID: PMC6344335          DOI: 10.1055/s-0038-1677043

Source DB:  PubMed          Journal:  Appl Clin Inform        ISSN: 1869-0327            Impact factor:   2.342


  5 in total

1.  A relational database for management of flow cytometry and ELISpot clinical trial data.

Authors:  James S Cavenaugh; Paul Snell; David Jeffries; Pauline A Waight; Samuel J McConkey
Journal:  Cytometry B Clin Cytom       Date:  2007-01-15       Impact factor: 3.058

2.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

3.  Design and implementation of decision support for tobacco dependence treatment in an inpatient electronic medical record: a randomized trial.

Authors:  Steven L Bernstein; June Rosner; Michelle DeWitt; Jeanette Tetrault; Allen L Hsiao; James Dziura; Scott Sussman; Patrick O'Connor; Benjamin Toll
Journal:  Transl Behav Med       Date:  2017-06       Impact factor: 3.046

4.  Managing data in surgical trials: a guide to modern-day data management systems.

Authors:  Paljinder Bhatti; Emil H Schemitsch; Mohit Bhandari
Journal:  J Bone Joint Surg Am       Date:  2012-07-18       Impact factor: 5.284

5.  The Cochrane Collaboration's tool for assessing risk of bias in randomised trials.

Authors:  Julian P T Higgins; Douglas G Altman; Peter C Gøtzsche; Peter Jüni; David Moher; Andrew D Oxman; Jelena Savovic; Kenneth F Schulz; Laura Weeks; Jonathan A C Sterne
Journal:  BMJ       Date:  2011-10-18
  5 in total
  1 in total

1.  Searching of Clinical Trials Made Easier in cBioPortal Using Patients' Genetic and Clinical Profiles.

Authors:  Philipp Unberath; Lukas Mahlmeister; Niklas Reimer; Hauke Busch; Melanie Boerries; Jan Christoph
Journal:  Appl Clin Inform       Date:  2022-03-30       Impact factor: 2.342

  1 in total

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