| Literature DB >> 30673132 |
Mehran Pashirzad1, Mojtaba Shafiee2, Amir Avan3,4, Mikhail Ryzhikov5, Hamid Fiuji6, Amirhossein Bahreyni7, Majid Khazaei8, Saman Soleimanpour9, Seyed Mahdi Hassanian1,3.
Abstract
Crocin is the major component of saffron, which is used in phytomedicine for the treatment of several diseases including diabetes, fatty liver, depression, menstruation disorders, and, of special interest in this review, inflammatory diseases. Promising selective anti-inflammatory properties of this pharmacological active component have been observed in several studies. Saffron has been shown to exert anti-inflammatory properties against several inflammatory diseases and can be used as a novel therapeutic agent for the treatment of inflammatory diseases either alone or in combination with other standard anti-inflammatory agents. This review summarizes the protective role of saffron and its pharmacologically active constituents in the pathogenesis of inflammatory diseases including digestive diseases, dermatitis, asthma, atherosclerosis, and neurodegenerative diseases for a better understanding and hence a better management of these diseases.Entities:
Keywords: crocin; inflammatory diseases; saffron
Year: 2019 PMID： 30673132 DOI： 10.1002/jcp.28177
Source DB: PubMed Journal: J Cell Physiol ISSN： 0021-9541 Impact factor: 6.384