Literature DB >> 30671603

Acute invasive fungal rhinosinusitis: our 2 year experience and outcome analysis.

Raghunath Shanbag1, Nita Rachel Rajan2, Arun Kumar1.   

Abstract

PURPOSE: The incidence of Acute invasive fungal rhinosinusitis (AIFRS) is on the rise considering the multitude of comorbidities present in a single patient.The delay in suspecting the fungal etiology, presentation of the patient for an Otorhinolaryngology consult and lack of defined protocols affects outcome.This study looks in to the various aspects of treatment of AIFRS including sample collection, diagnosis and medicosurgical treatment. We propose a protocol for the management of these patients crafted from our outcome.
METHODS: Between September 2015-September 2017, 14 patients presented with AIFRS. Targeted samples were taken for Potassium hydroxide mount, histopathological studies and fungal culture. Management was initiated with antifungals and multi-approach surgical debridement.
RESULTS: Six of these patients had multiple comorbidities and most were uncontrolled diabetics. The average delay in presentation was 9 days. Potassium hydroxide mount was the screening test of choice. A minimum of two sittings of debridement was essential. In an average follow-up period of 15.12 months, all the patients are alive and disease free.
CONCLUSION: A high index of suspicion, awareness among medical fraternity and precise sample collection aids a firm diagnosis. Simultaneous initiation of surgical debridement and anti-fungals is fundamental.

Entities:  

Keywords:  Diabetes mellitus; Invasive fungal rhinosinusitis; Liposomal amphotericin B; Mucormycosis; Outcome

Mesh:

Substances:

Year:  2019        PMID: 30671603     DOI: 10.1007/s00405-019-05288-w

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  11 in total

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Authors:  Fikret Kasapoglu; Hakan Coskun; Omer Afsin Ozmen; Halis Akalin; Beyza Ener
Journal:  Otolaryngol Head Neck Surg       Date:  2010-11       Impact factor: 3.497

2.  A prospective study of mucormycosis in north India: experience from a tertiary care hospital.

Authors:  Kiran Bala; Jagdish Chander; Uma Handa; Rajpal Singh Punia; Ashok Kumar Attri
Journal:  Med Mycol       Date:  2015-01-13       Impact factor: 4.076

3.  Rhinocerebral mucormycosis: a retrospective study.

Authors:  Jyoti Shailesh Kolekar
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2014-12-05

4.  Invasive fungal rhinosinusitis: a 15-year experience with 29 patients.

Authors:  Marcus M Monroe; Max McLean; Nathan Sautter; Mark K Wax; Peter E Andersen; Timothy L Smith; Neil D Gross
Journal:  Laryngoscope       Date:  2013-02-16       Impact factor: 3.325

5.  A mucormycosis case treated with a combination of caspofungin and amphotericin B.

Authors:  E Kazak; E Aslan; H Akalın; O Saraydaroğlu; B Hakyemez; L Erişen; B Yazıcı; E Gürcüoğlu; E Yılmaz; B Ener; S Helvacı
Journal:  J Mycol Med       Date:  2013-07-12       Impact factor: 2.391

6.  Prognostic factors for survival in patients with acute invasive fungal rhinosinusitis.

Authors:  Hyun-Jin Cho; Min-Seok Jang; Sang Duk Hong; Seung-Kyu Chung; Hyo Yeol Kim; Hun-Jong Dhong
Journal:  Am J Rhinol Allergy       Date:  2015 Jan-Feb       Impact factor: 2.467

7.  Invasive fungal sinusitis: a 15-year review from a single institution.

Authors:  Shatul L Parikh; Giridhar Venkatraman; John M DelGaudio
Journal:  Am J Rhinol       Date:  2004 Mar-Apr

8.  Acute Invasive Fungal Rhinosinusitis: A 15-Year Experience with 41 Patients.

Authors:  Sakeena J Payne; Ron Mitzner; Sudhir Kunchala; Lauren Roland; Johnathan D McGinn
Journal:  Otolaryngol Head Neck Surg       Date:  2016-02-16       Impact factor: 3.497

Review 9.  Survival outcomes in acute invasive fungal sinusitis: a systematic review and quantitative synthesis of published evidence.

Authors:  Justin H Turner; Ethan Soudry; Jayakar V Nayak; Peter H Hwang
Journal:  Laryngoscope       Date:  2013-01-08       Impact factor: 3.325

10.  The successful use of amphotericin B followed by oral posaconazole in a rare case of invasive fungal sinusitis caused by co-infection with mucormycosis and aspergillus.

Authors:  Sharana Mahomed; Sujith Basanth; Koleka Mlisana
Journal:  IDCases       Date:  2015-10-28
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  2 in total

1.  Definition and management of invasive fungal rhinosinusitis: a single-centre retrospective study.

Authors:  Gian Luca Fadda; Federica Martino; Giacomo Andreani; Giovanni Succo; Maurizio Catalani; Stefano Di Girolamo; Giovanni Cavallo
Journal:  Acta Otorhinolaryngol Ital       Date:  2021-02       Impact factor: 2.124

2.  Clinical and surgical factors affecting the prognosis and survival rates in patients with mucormycosis.

Authors:  Harun Gür; Onur İsmi; Yusuf Vayısoğlu; Kemal Görür; Rabia Bozdoğan Arpacı; Elif Şahin Horasan; Cengiz Özcan
Journal:  Eur Arch Otorhinolaryngol       Date:  2021-06-01       Impact factor: 2.503

  2 in total

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