Literature DB >> 30671244

Isometric knee extension force in Japanese type 2 diabetic patients without apparent diabetic polyneuropathy: Data from the Multicenter Survey of the Isometric Lower Extremity Strength in Type 2 Diabetes study.

Takuo Nomura1, Tomoyasu Ishiguro2,3, Masayoshi Ohira4, Hiroyuki Oka5, Yukio Ikeda6.   

Abstract

OBJECTIVES: To determine standard reference values for isometric knee extension force using a cohort of Japanese type 2 diabetic patients without diabetic polyneuropathy.
METHODS: Patient data were collected from the Multicenter Survey of the Isometric Lower Extremity Strength in Type 2 Diabetes study and compared with previously published data of healthy control subjects. In total, we enrolled 898 patients with type 2 diabetes aged 30-87 years, who did not have diabetic polyneuropathy. The control group included 510 healthy subjects aged 30-88 years. Maximum isometric knee extension force (KEF) values were obtained by using a hand-held dynamometer with belt stabilization. In addition, KEF (kgf) was adjusted for bodyweight (kg) to calculate %KEF.
RESULTS: KEF and %KEF decreased with age in both patients with diabetes and healthy control subjects. The mean values of KEF and %KEF in patients with diabetes were reduced by 9.7% and 20.8%, respectively, in males, and by 11.6% and 23.0%, respectively, in females compared to the values in healthy control subjects.
CONCLUSION: KEF and %KEF in patients with type 2 diabetes without diabetic polyneuropathy may reduce by approximately 10% and 20%, respectively, compared to these values in healthy control subjects. This study provides reference values for isometric KEF with respect to sex in a population covering a wide age range.

Entities:  

Keywords:  Knee extension force; reference value; type 2 diabetes

Year:  2019        PMID: 30671244      PMCID: PMC6329036          DOI: 10.1177/2050312118823412

Source DB:  PubMed          Journal:  SAGE Open Med        ISSN: 2050-3121


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