Literature DB >> 30670245

The occurrence of acetaminophen/codeine as an adulterant in herbal analgesic supplements in Hamadan, Iran: A pilot study.

Amir Nili-Ahmadabadi1, Zahra Borzouee1, Davoud Ahmadimoghaddam1, Farzin Firozian2, Dara Dastan3.   

Abstract

Analgesics, such as acetaminophen (APAP) and codeine (COD), are used to adulterate medicinal herbs and/or herbal supplements. This study evaluated the APAP and COD levels in 60 herbal supplement and/or herb-based medicine samples collected from apothecaries in Hamadan, Iran. The samples were analysed using a high-performance liquid chromatography (HPLC) system. The results showed that 15% of the samples contained 38900-165200 ng/g and 31.1-603.3 ng/g of APAP and COD, respectively. Due to the side-effects of analgesic drugs in human, control of these drugs is recommended in herbal supplements.
Copyright © 2018. Published by Elsevier Ltd.

Entities:  

Keywords:  Acetaminophen; Analgesics; Codeine; HPLC; Herbal supplements

Mesh:

Substances:

Year:  2018        PMID: 30670245     DOI: 10.1016/j.ctim.2018.11.018

Source DB:  PubMed          Journal:  Complement Ther Med        ISSN: 0965-2299            Impact factor:   2.446


  4 in total

1.  A Behavioral Study of Promethazine Interaction with Analgesic Effect of Diclofenac: Pain Combination Therapy.

Authors:  Niloofar Amidi; Zohreh Izadidastenaei; Malihe Araghchian; Davoud Ahmadimoghaddam
Journal:  J Pharmacopuncture       Date:  2020-03-31

2.  Allium Jesdianum Extract Improve Acetaminophen-Induced Hepatic Failure through Inhibition of Oxidative/Nitrosative Stress.

Authors:  Zohreh Sohrabinezhad; Dara Dastan; Sara Soleimani Asl; Amir Nili-Ahmadabadi
Journal:  J Pharmacopuncture       Date:  2019-12-31

3.  Antinociceptive activity of Cnicus benedictus L. leaf extract: a mechanistic evaluation.

Authors:  Davoud Ahmadimoghaddam; Reihaneh Sadeghian; Akram Ranjbar; Zohreh Izadidastenaei; Saeed Mohammadi
Journal:  Res Pharm Sci       Date:  2020-10-19

4.  Adulteration of the Herbal Weight Loss Products by the Illegal Addition of Synthetic Antiobesity Medications: A Pilot Study.

Authors:  Farzin Firozian; Amir Nili-Ahmadabadi; Shirin Moradkhani; Miad Moulaei; Zohreh Fasihi; Davoud Ahmadimoghaddam
Journal:  J Obes       Date:  2021-07-14
  4 in total

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