Literature DB >> 3066646

Clofazimine in dermatitis ulcerosa (pyoderma gangrenosum). Open clinical trial.

H Mensing1.   

Abstract

Five patients suffering from dermatitis ulcerosa (a variant of pyoderma gangrenosum) were treated with clofazimine in a daily dosage of 200 mg orally. Complete healing was noted in 2 patients, partial response in 2, no effect in 1. Side effects were mild and transitory in form of a red coloring of the skin (all patients) and mild ichthyosis (2 patients).

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Year:  1988        PMID： 3066646     DOI： 10.1159/000248569

Source DB:  PubMed          Journal:  Dermatologica        ISSN： 0011-9075


  3 in total

1.  [Differential diagnosis of "sterile" phlegmonous hand infections].

Authors:  A Daigeler; M Lehnhardt; M Helwing; L Steinstraesser; H-H Homann; H-U Steinau; D Druecke
Journal:  Chirurg       Date:  2006-11       Impact factor: 0.955

2.  Superficial Variant of Pyoderma Gangrenosum Successfully Treated with Lower Dose Clofazimine.

Authors:  Alaka J Mohan; Sunitha Balakrishnan; Betsy Ambooken; Kidangazhiathmana Ajithkumar; Neelakandhan Asokan
Journal:  Indian Dermatol Online J       Date:  2022-01-24

3.  Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes.

Authors:  Yunzhao R Ren; Fan Pan; Suhel Parvez; Andrea Fleig; Curtis R Chong; Jing Xu; Yongjun Dang; Jin Zhang; Hongsi Jiang; Reinhold Penner; Jun O Liu
Journal:  PLoS One       Date:  2008-12-23       Impact factor: 3.240
  3 in total

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