Literature DB >> 3066616

Children of school age: the influence of antiepileptic drugs on behavior and intellect.

M R Trimble1, C Cull.   

Abstract

The role of antiepileptic drugs in behavior and cognitive function in children is well documented in the literature. In general, behavioral problems occur most frequently with phenobarbital and clonazepam, and appear least often with valproate and carbamazepine. Cognitive impairments occur with phenytoin, are less evident with valproate, and minimal with carbamazepine. Monotherapy, as with adults, leads to improvements in both cognitive abilities and behavior.

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Year:  1988        PMID: 3066616     DOI: 10.1111/j.1528-1157.1988.tb05805.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  12 in total

Review 1.  Phenobarbitone versus phenytoin monotherapy for epilepsy: an individual participant data review.

Authors:  Sarah J Nevitt; Catrin Tudur Smith; Anthony G Marson
Journal:  Cochrane Database Syst Rev       Date:  2019-07-31

Review 2.  Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.

Authors:  Sarah J Nevitt; Maria Sudell; Jennifer Weston; Catrin Tudur Smith; Anthony G Marson
Journal:  Cochrane Database Syst Rev       Date:  2017-06-29

Review 3.  Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review.

Authors:  Sarah J Nolan; Anthony G Marson; Jennifer Weston; Catrin Tudur Smith
Journal:  Cochrane Database Syst Rev       Date:  2016-12-15

Review 4.  Neurocognitive Effects of Antiseizure Medications in Children and Adolescents with Epilepsy.

Authors:  Frank M C Besag; Michael J Vasey
Journal:  Paediatr Drugs       Date:  2021-05-06       Impact factor: 3.022

5.  Childhood Epilepsy : Current Therapeutic Recommendations.

Authors:  J T Gilman; M Duchowny
Journal:  CNS Drugs       Date:  1994-03       Impact factor: 5.749

6.  Neuropsychological profile of adult patients with nonsymptomatic occipital lobe epilepsies.

Authors:  Leonilda Bilo; Gabriella Santangelo; Ilaria Improta; Carmine Vitale; Roberta Meo; Luigi Trojano
Journal:  J Neurol       Date:  2012-08-18       Impact factor: 4.849

7.  Psychological effects of sodium valproate and carbamazepine in epilepsy.

Authors:  G Stores; P L Williams; E Styles; Z Zaiwalla
Journal:  Arch Dis Child       Date:  1992-11       Impact factor: 3.791

Review 8.  Drug Treatment of Epilepsy Neuropsychiatric Comorbidities in Children.

Authors:  Gregory L Holmes
Journal:  Paediatr Drugs       Date:  2020-11-24       Impact factor: 3.022

Review 9.  Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.

Authors:  Sarah J Nevitt; Maria Sudell; Jennifer Weston; Catrin Tudur Smith; Anthony G Marson
Journal:  Cochrane Database Syst Rev       Date:  2017-12-15

10.  Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review.

Authors:  Sarah J Nevitt; Anthony G Marson; Catrin Tudur Smith
Journal:  Cochrane Database Syst Rev       Date:  2018-10-24
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