Michael Holzer1, Gunther Marsche2,3. 1. Division of Pharmacology, Otto Loewi Research Centre, Medical University of Graz, Graz, Austria michael.holzer@medunigraz.at. 2. Division of Pharmacology, Otto Loewi Research Centre, Medical University of Graz, Graz, Austria. 3. BioTechMed-Graz, Graz, Austria.