Silvia Gálvez-Pastor1, Nuria M Torregrosa1, Antonio Ríos2, Beatriz Febrero2, Rafael González-Costea1, María A García-López1, María D Balsalobre1, Patrícia Pastor-Pérez3, Pablo Moreno4, José L Vázquez-Rojas1, José M Rodríguez5. 1. Servicio de Cirugía General y del Aparato Digestivo, Hospital Universitario Santa Lucía, Cartagena, Murcia, Spain. 2. Servicio de Cirugía General y del Aparato Digestivo, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain; Departamento de Cirugía, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Murcia, Spain. 3. Servicio de Cirugía General y del Aparato Digestivo, Hospital General Universitario Reina Sofía, Murcia, Spain. 4. Servicio de Cirugía General y Digestivo, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain. 5. Servicio de Cirugía General y del Aparato Digestivo, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain; Departamento de Cirugía, Facultad de Medicina, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), Murcia, Spain. Electronic address: jmrodri@um.es.
Abstract
BACKGROUND: Hypocalcemia is one of the most common complications after total thyroidectomy. Recently, indocyanine green (ICG) angiography of the parathyroid glands (PGs) has been suggested as a reliable tool for predicting postoperative hypocalcemia. The aim of our study was to evaluate the performance of a simple quantitative score based on ICG angiography of the PGs (4-ICG score) for predicting postoperative hypocalcemia. METHODS: Thirty nine consecutive patients who underwent total thyroidectomy for multinodular goiter were included. For each patient, the 4-ICG score was calculated, adding the individual viability value of the four PGs. Discrimination and correlation analyses were performed. RESULTS: In 32/39 patients, the four PGs were identified. Patients with postoperative hypocalcemia (n = 6, 19%) had a lower 4-ICG score (2.5 [1.8-3.3] vs. 4.0 [3.0-6.0]; p = 0.003). The 4-ICG score showed good discrimination in terms of predicting postoperative hypocalcemia (AUC = 0.875 (0.710-0.965); p = 0.001) and a good correlation with postoperative parathyroid function. CONCLUSIONS: The 4-ICG score predicts postoperative hypocalcemia and correlates well with postoperative parathyroid function in patients undergoing total thyroidectomy for multinodular goiter.
BACKGROUND:Hypocalcemia is one of the most common complications after total thyroidectomy. Recently, indocyanine green (ICG) angiography of the parathyroid glands (PGs) has been suggested as a reliable tool for predicting postoperative hypocalcemia. The aim of our study was to evaluate the performance of a simple quantitative score based on ICG angiography of the PGs (4-ICG score) for predicting postoperative hypocalcemia. METHODS: Thirty nine consecutive patients who underwent total thyroidectomy for multinodular goiter were included. For each patient, the 4-ICG score was calculated, adding the individual viability value of the four PGs. Discrimination and correlation analyses were performed. RESULTS: In 32/39 patients, the four PGs were identified. Patients with postoperative hypocalcemia (n = 6, 19%) had a lower 4-ICG score (2.5 [1.8-3.3] vs. 4.0 [3.0-6.0]; p = 0.003). The 4-ICG score showed good discrimination in terms of predicting postoperative hypocalcemia (AUC = 0.875 (0.710-0.965); p = 0.001) and a good correlation with postoperative parathyroid function. CONCLUSIONS: The 4-ICG score predicts postoperative hypocalcemia and correlates well with postoperative parathyroid function in patients undergoing total thyroidectomy for multinodular goiter.
Authors: Pablo Moreno-Llorente; Arantxa García-Barrasa; Mireia Pascua-Solé; Sebastián Videla; Aurema Otero; José Luis Muñoz-de Nova Journal: World J Surg Date: 2022-08-09 Impact factor: 3.282
Authors: S Priyanka; Shawn Thomas Sam; Grace Rebekah; Supriya Sen; Varghese Thomas; Syrpailyne Wankhar; Anish Jacob Cherian; Deepak Thomas Abraham; Mazuvanchary Jacob Paul Journal: Updates Surg Date: 2021-11-02
Authors: Emmanuel A Mannoh; Giju Thomas; Naira Baregamian; Sarah L Rohde; Carmen C Solórzano; Anita Mahadevan-Jansen Journal: Thyroid Date: 2021-08-18 Impact factor: 6.506
Authors: Eline A Feitsma; Hugo M Schouw; Milou E Noltes; Wido Heeman; Wendy Kelder; Gooitzen M van Dam; Schelto Kruijff Journal: Life (Basel) Date: 2022-03-08