Clever Gomes1, Adriana B Almeida2, Ana C Rosa2, Perla F Araujo2, Antonio R L Teixeira3. 1. Laboratory of Morphology and Morphogenesis, Institute of Biology, Federal University of Goiás, Goiânia, Brazil. 2. Chagas Disease Multidisciplinary Research Laboratory, Faculty of Medicine, University of Brasília, Federal District, 70910-900, Brazil. 3. Chagas Disease Multidisciplinary Research Laboratory, Faculty of Medicine, University of Brasília, Federal District, 70910-900, Brazil. Electronic address: antonioteixeirarl@gmail.com.
Abstract
OBJECTIVE: To contribute to the discussion on the research findings indicating the sexual transmission of American trypanosomiasis and Chagas disease in humans. METHODS: A review of the literature was performed to investigate the routes of transmission of Trypanosoma cruzi parasites and to evaluate the distribution of Chagas disease, which is now found across five continents. RESULTS: The epidemiological profile of American trypanosomiasis, which is still considered a neglected disease of the poor people of Latin America, has changed over time. A family-based study demonstrated that the blood protozoan T. cruzi can be transmitted sexually from infected males and females to naïve mates. CONCLUSIONS: Evidence that Chagas disease can be transmitted sexually, coupled with the migration of individuals with Chagas disease to previously non-endemic countries and increased travel to endemic countries, has implications for public health. Improved screening of blood supplies and prenatal care are required to prevent congenital spread.
OBJECTIVE: To contribute to the discussion on the research findings indicating the sexual transmission of American trypanosomiasis and Chagas disease in humans. METHODS: A review of the literature was performed to investigate the routes of transmission of Trypanosoma cruzi parasites and to evaluate the distribution of Chagas disease, which is now found across five continents. RESULTS: The epidemiological profile of American trypanosomiasis, which is still considered a neglected disease of the poor people of Latin America, has changed over time. A family-based study demonstrated that the blood protozoan T. cruzi can be transmitted sexually from infected males and females to naïve mates. CONCLUSIONS: Evidence that Chagas disease can be transmitted sexually, coupled with the migration of individuals with Chagas disease to previously non-endemic countries and increased travel to endemic countries, has implications for public health. Improved screening of blood supplies and prenatal care are required to prevent congenital spread.
Authors: Alexei Y Kostygov; Anna Karnkowska; Jan Votýpka; Daria Tashyreva; Kacper Maciszewski; Vyacheslav Yurchenko; Julius Lukeš Journal: Open Biol Date: 2021-03-10 Impact factor: 6.411
Authors: Verônica da Silva Oliveira; Elen Diana Dantas; Anna Thereza de Sousa Queiroz; Johny Wysllas de Freitas Oliveira; Marcelo de Sousa da Silva; Patricia Garcia Ferreira; Fernando de Carvalho da Siva; Vitor Francisco Ferreira; Ádley Antonini Neves de Lima Journal: Pharmaceutics Date: 2020-11-24 Impact factor: 6.321