| Literature DB >> 30664678 |
Hao Yin1,2, Wen Xue3,4,5, Daniel G Anderson6,7,8,9.
Abstract
In the past decade, the development of a genome-editing technology mediated by CRISPR has made genetic engineering easier than ever, both in vitro and in vivo. CRISPR systems have enabled important advances in cancer research by accelerating the development of study models or as a tool in genetic screening studies, including those aiming to discover and validate therapeutic targets. In this Review, we discuss these applications as well as new potential uses of CRISPR to assist in cancer detection or the development of anticancer therapies.Entities:
Mesh：
Year: 2019 PMID： 30664678 DOI： 10.1038/s41571-019-0166-8
Source DB: PubMed Journal: Nat Rev Clin Oncol ISSN： 1759-4774 Impact factor: 66.675