Literature DB >> 30663368

A new diterpenoid alkaloid from Aconitum hemsleyanum.

Zhi-Hui Luo1, Yang Chen1, Xin-Yi Sun1, Hua Fan1, Wei Li2, Liang Deng2, Tian-Peng Yin1.   

Abstract

A new C19-diterpenoid alkaloid named hemsleyaline (1), along with fourteen known alkaloids (2-15), were isolated from the roots of Aconitum hemsleyanum Pritz. (Ranunculaceae), a herbal medicine in southwest China. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 showed mild cholinesterase inhibitory effect with IC50 value of 471 ± 9 μM.

Entities:  

Keywords:  Aconitum hemsleyanum; Ranunculaceae; cholinesterase inhibitory effect; diterpenoid alkaloid

Year:  2019        PMID： 30663368     DOI： 10.1080/14786419.2018.1560292

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  1 in total

1.  Isoquinoline Alkaloid Contents in Macleaya cordata Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition.

Authors:  Tomasz Tuzimski; Anna Petruczynik; Małgorzata Szultka-Młyńska; Mateusz Sugajski; Bogusław Buszewski
Journal:  Molecules       Date:  2022-06-03       Impact factor: 4.927
  1 in total

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