Literature DB >> 30662672

Drug discovery and drug marketing with the critical roles of modern administration.

Jing Chen1, Xiaofang Luo2, Huimin Qiu2, Vienna Mackey3, Lichun Sun4,3, Xiaoping Ouyang1.   

Abstract

Drug research and development is a long-term and complicated process with the involvement of multidisciplinary, multi-sector cooperation and regulations of the Food and Drug Administration (FDA). It is of high risk, high cost, high benefit and time-consuming. Therefore, the drug administration and management is extremely necessary and useful. We discussed the whole process including laboratory study, target determination, drug discovery and screening, leading compound and optimization, preclinical and clinical trials, FDA approval and marketing. Actively exploring and applying modern administration and innovative management technology, we can scientifically and effectively enhance the discovery of new drug research and development, and strengthen the supervision of drug market. In recent years, innovation such as artificial intelligence has been applied to drug discovery and drug administration. We further analyzed the possibility of applying management technology to reduce risks, generate profits and benefit patients in the whole process of new drug research and development. In conclusion, drug administration and management plays critical roles in modern drug research and development, and the new technology can be helpful for drug launching.

Entities:  

Keywords:  Drug research and development; administration; laboratory; management; preclinical and clinical trial

Year:  2018        PMID: 30662672      PMCID: PMC6325519     

Source DB:  PubMed          Journal:  Am J Transl Res            Impact factor:   4.060


  5 in total

1.  Treatment Access, Health Economics, and the Wave of a Magic Wand.

Authors:  David J Stewart; John-Peter Bradford; Gerald Batist
Journal:  Curr Oncol       Date:  2022-02-16       Impact factor: 3.677

2.  Fenbendazole Controls In Vitro Growth, Virulence Potential, and Animal Infection in the Cryptococcus Model.

Authors:  Haroldo C de Oliveira; Luna S Joffe; Karina S Simon; Rafael F Castelli; Flavia C G Reis; Arielle M Bryan; Beatriz S Borges; Lia C Soares Medeiros; Anamelia L Bocca; Maurizio Del Poeta; Marcio L Rodrigues
Journal:  Antimicrob Agents Chemother       Date:  2020-05-21       Impact factor: 5.191

Review 3.  Extent, reasons and consequences of off-labeled and unlicensed drug prescription in hospitalized children: a narrative review.

Authors:  Wasim Shuib; Xin-Yin Wu; Fang Xiao
Journal:  World J Pediatr       Date:  2021-06-02       Impact factor: 2.764

4.  Preparation, urease inhibition mechanisms, and anti-Helicobacter pylori activities of hesperetin-7-rhamnoglucoside.

Authors:  Mohamed Sharaf; Muhammad Arif; Hamed I Hamouda; Sohaib Khan; Mohnad Abdalla; Samah Shabana; Hussein E Rozan; Tehsin Ullah Khan; Zhe Chi; Chenguang Liu
Journal:  Curr Res Microb Sci       Date:  2021-12-29

5.  Acute oral toxicity assessment of ethanolic extracts of Antidesma bunius (L.) Spreng fruits in mice.

Authors:  Maria Nilda M Muñoz; Urdujah G Alvarado; Jerica Isabel L Reyes; Kozo Watanabe
Journal:  Toxicol Rep       Date:  2021-06-17
  5 in total

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