| Literature DB >> 30662050 |
Akito Ito1, Ryo Takata1, Teppei Matsuo2, Toshimoto Kimura2, Kouki Otsuka2, Shuhei Ishii1, Suguru Tokiwa3, Susumu Tanji4, Jun Sugimura1, So Omori1, Wataru Obara1.
Abstract
A 45-years-old man presented discharge of abscess from the umbilicus with lower abdominal pain. CT scan showed huge tumor from the bladder to the umbilical part with sigmoid colon invasion. He was diagnosed as urachal carcinoma, which was confirmed by pathological examination. We started FOLFOX chemotherapy according to advanced colon cancer. Approximately 80% of reduction was accomplished after 11 courses of FOLFOX. We performed radical cystectomy with sigmoid colon resection. Pathological examination revealed complete resection with negative surgical margin. No recurrence and metastasis were observed after 30 months of surgery. Urachal carcinoma is often advanced cancer when diagnosed. Effective chemotherapy is not established well. FOLFOX chemotherapy demonstrated the well antitumor effect in this case.Entities:
Keywords: FOLFOX chemotherapy; Gene polymorphism; Urachal carcinoma
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Year: 2018 PMID: 30662050 DOI: 10.5980/jpnjurol.109.35
Source DB: PubMed Journal: Nihon Hinyokika Gakkai Zasshi ISSN: 0021-5287