Literature DB >> 30661473

Costimulatory pathway targets for autoimmune and inflammatory conditions: clinical successes, failures, and hope for the future.

Pamela Spicer1, Laura Runkel1.   

Abstract

Keywords:  Autoimmune diseases; CD28; CD40; ICOS; OX40; costimulatory signals

Mesh：

Year:  2019        PMID： 30661473     DOI： 10.1080/13543784.2019.1557146

Source DB:  PubMed          Journal:  Expert Opin Investig Drugs        ISSN： 1354-3784            Impact factor:   6.206


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  4 in total

1.  Cytotoxic T lymphocyte antigen-4 regulates development of xenogenic graft versus host disease in mice via modulation of host immune responses induced by changes in human T cell engraftment and gene expression.

Authors:  Chunxu Gao; Debra Gardner; Marie-Clare Theobalds; Shannon Hitchcock; Heather Deutsch; Chidozie Amuzie; Matteo Cesaroni; Davit Sargsyan; Tadimeti S Rao; Ravi Malaviya
Journal:  Clin Exp Immunol       Date:  2021-09-22       Impact factor: 4.330

2.  Safety and Biological Activity of Rozibafusp alfa, a Bispecific Inhibitor of Inducible Costimulator Ligand and B Cell Activating Factor, in Patients With Rheumatoid Arthritis: Results of a Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study.

Authors:  Lubna Abuqayyas; Laurence E Cheng; Marcia Teixeira Dos Santos; Barbara A Sullivan; Norma Ruiz-Santiago; Hui Wang; Yanchen Zhou; Vishala Chindalore; Stanley Cohen; Alan J Kivitz; Maximilian G Posch; Jane R Parnes
Journal:  ACR Open Rheumatol       Date:  2022-07-27

3.  Anti-C5 Antibody Tesidolumab Reduces Early Antibody-mediated Rejection and Prolongs Survival in Renal Xenotransplantation.

Authors:  Andrew B Adams; Brendan P Lovasik; David A Faber; Christopher Burlak; Cynthia Breeden; Jose L Estrada; Luz M Reyes; Rodrigo M Vianna; Matthew F Tector; Alfred J Tector
Journal:  Ann Surg       Date:  2021-09-01       Impact factor: 13.787

4.  Multimarker profiling identifies protective and harmful immune processes in heart failure: findings from BIOSTAT-CHF.

Authors:  George Markousis-Mavrogenis; Jasper Tromp; Wouter Ouwerkerk; João Pedro Ferreira; Stefan D Anker; John G Cleland; Kenneth Dickstein; Gerasimos Filippatos; Chim C Lang; Marco Metra; Nilesh J Samani; Rudolf A de Boer; Dirk J van Veldhuisen; Adriaan A Voors; Peter van der Meer
Journal:  Cardiovasc Res       Date:  2022-06-29       Impact factor: 13.081
  4 in total

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