Danila L Nunes-Dos-Santos1, Samira V Gomes1, Vandilson P Rodrigues1,2, Antonio L A Pereira1,3. 1. Dentistry Graduate Program, Federal University of Maranhão, São Luís, Maranhão, Brazil. 2. Department of Morphology, Federal University of Maranhão, São Luís, Maranhão, Brazil. 3. Department of Dentistry II, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Abstract
OBJECTIVE: The aim of this systematic review was to identify clinical outcomes following kidney transplantation associated with periodontal status. MATERIAL AND METHODS: A systematic review was conducted and included cross-sectional, case-control, or cohort studies published until August 2018 from PubMed/MEDLINE, Scopus, Science Direct, and CENTRAL. The research was carried out using the following descriptors: "kidney transplantation," "chronic renal failure," "periodontal diseases," "periodontitis," "chronic periodontitis," "gingival hyperplasia," and "gingivitis." The outcomes comprised the clinical transplantation variables. Two independent reviewers extracted the data and assessed the quality of the studies using Newcastle-Ottawa scale. RESULTS: The electronic search revealed 1,063 potentially relevant studies. We selected 114 articles for reading the full text. Therefore, six studies met the inclusion criteria: one case-control, three cross-sectional, and two cohort studies. All studies showed low risk of bias. The findings suggest that the periodontal status may be associated with the largest left ventricular mass, greater carotid thickness, graft rejection, lower graft survival, and a higher mortality rate within 60 months among kidney transplant recipients. CONCLUSION: The findings of this systematic review indicate that there is an association between periodontal status and worsening of graft function and systemic health among kidney transplant recipients.
OBJECTIVE: The aim of this systematic review was to identify clinical outcomes following kidney transplantation associated with periodontal status. MATERIAL AND METHODS: A systematic review was conducted and included cross-sectional, case-control, or cohort studies published until August 2018 from PubMed/MEDLINE, Scopus, Science Direct, and CENTRAL. The research was carried out using the following descriptors: "kidney transplantation," "chronic renal failure," "periodontal diseases," "periodontitis," "chronic periodontitis," "gingival hyperplasia," and "gingivitis." The outcomes comprised the clinical transplantation variables. Two independent reviewers extracted the data and assessed the quality of the studies using Newcastle-Ottawa scale. RESULTS: The electronic search revealed 1,063 potentially relevant studies. We selected 114 articles for reading the full text. Therefore, six studies met the inclusion criteria: one case-control, three cross-sectional, and two cohort studies. All studies showed low risk of bias. The findings suggest that the periodontal status may be associated with the largest left ventricular mass, greater carotid thickness, graft rejection, lower graft survival, and a higher mortality rate within 60 months among kidney transplant recipients. CONCLUSION: The findings of this systematic review indicate that there is an association between periodontal status and worsening of graft function and systemic health among kidney transplant recipients.
Authors: Maja Dodig Novaković; Sanja Lovrić Kojundžić; Mislav Radić; Marijana Vučković; Andrea Gelemanović; Marija Roguljić; Katja Kovačević; Josip Orešković; Josipa Radić Journal: J Pers Med Date: 2022-06-16
Authors: Josipa Radić; Marijana Vučković; Andrea Gelemanović; Marija Roguljić; Josip Orešković; Katja Kovačević; Ela Kolak; Dora Bučan Nenadić; Mislav Radić Journal: Sci Rep Date: 2022-07-08 Impact factor: 4.996
Authors: Zhaodan Xin; Lijuan Wu; Juan Zhou; Jie Zhuang; Wu Peng; Turun Song; Tao Lin; Xiaojun Lu; Binwu Ying Journal: Front Med (Lausanne) Date: 2020-11-12
Authors: Samira V Gomes; Vandilson Rodrigues; Danila L Nunes-Dos-Santos; Antonio L A Pereira; Marco A Peres Journal: Clin Oral Investig Date: 2021-07-01 Impact factor: 3.573