Literature DB >> 30659767

Open source code for behavior analysis in rodents.

Satoko Hattori1, Yoshihiro Okumura2, Keizo Takao3, Yoko Yamaguchi2, Tsuyoshi Miyakawa1.   

Abstract

AIM: We have conducted a series of behavioral tests, which cover a broad range of behavioral domains, on various strains of genetically engineered mice. For the behavioral screening, we have been using Image J plugins that we developed for most of the tests in the battery. Our behavioral analysis system with the plugins enables systematic and automated image analysis of behavior. The plugins are freely available on the "Mouse Phenotype Database" website (http://www.mouse-phenotype.org/software.html). Here, we release the source code of the plugins in a Git repository with the aim of promoting their use and expanding their functionality.
METHODS: We published the source code of the Image J plugins for behavioral analysis at Git repository (https://github.com/neuroinformatics). The source code for light/dark transition, elevated plus maze, open filed, T-maze, and fear conditioning tests was made publicly available in the repository.
CONCLUSIONS: The source code of the plugins for the behavioral tests as well as the pre-compiled binaries can be freely obtained. The open source code could promote the development and modification of the plugins for additional behavioral indices in these tests and for other behavioral tests.
© 2019 The Authors. Neuropsychopharmacology Reports published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Neuropsychopharmacology.

Entities:  

Keywords:  Image J; comprehensive behavioral test battery; open source code

Year:  2019        PMID: 30659767     DOI: 10.1002/npr2.12047

Source DB:  PubMed          Journal:  Neuropsychopharmacol Rep        ISSN: 2574-173X


  3 in total

1.  Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain.

Authors:  Atsuki Kawamura; Yoshifumi Abe; Fumiko Seki; Yuta Katayama; Masaaki Nishiyama; Norio Takata; Kenji F Tanaka; Hideyuki Okano; Keiichi I Nakayama
Journal:  Mol Brain       Date:  2020-11-23       Impact factor: 4.041

2.  Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J mice: a challenge against conventional interpretation of the test.

Authors:  Hirotaka Shoji; Tsuyoshi Miyakawa
Journal:  Mol Brain       Date:  2021-02-15       Impact factor: 4.041

3.  Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning.

Authors:  Michiko Shirane; Hirotaka Shoji; Yutaka Hashimoto; Hiroyuki Katagiri; Shizuka Kobayashi; Toshiya Manabe; Tsuyoshi Miyakawa; Keiichi I Nakayama
Journal:  Mol Brain       Date:  2020-11-10       Impact factor: 4.041

  3 in total

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