Literature DB >> 30659742

What is the outcome for patients undergoing more than two ileocolonic resections for recurrent Crohn's disease? A comparative study of 569 consecutive procedures.

M Bouquot1, L Maggiori1, E Hain1, J Prost A la Denise1, Y Bouhnik2, Y Panis1.   

Abstract

AIM: To assess the outcome for patients undergoing repeated ileocolonic resection for recurrent Crohn's disease (CD).
METHOD: All patients undergoing ileocolonic resection for terminal ileal CD between 1998 and 2016 in our tertiary care centre were retrospectively reviewed.
RESULTS: Between 1998 and 2016, 569 ileocolonic resections were performed for CD: 403 of these were primary resections (1R, 71%), 107 second resections (2R, 19%) and 59 were third (or more) resections (> 2R, 10%). The laparoscopic approach rate was significantly less in the > 2R group (20/59, 34%) compared with the 2R (71/107, 66%; P = 0.002) and 1R (366/403, 91%) groups. However, conversion to an open approach did not show any difference between the three groups [1R group 46/366 (13%) vs 2R group 14/71 (20%) vs > 2R group 3/20 (15%); 1R vs > 2R P = 0.750; 2R vs > 2R P = 0.633]. Postoperative morbidity was significantly increased in the > 2R (28/59, 52%) group compared with the 1R group (115/403, 29%; P < 0.001) but showed no difference compared with the 2R group (43/107, 40%; P = 0.365). There was no difference between the groups in the incidence of severe postoperative morbidity (Clavien-Dindo ≥ 3) [1R group n = 24 (6%); 2R group n = 6 (6%); > 2R group n = 4, 7%; 1R vs > 2R P = 0.865, 2R vs > 2R P = 0.761].
CONCLUSION: Although the overall morbidity rate was higher, repeated surgery for recurrent CD in patients undergoing three or more ileocolonic resections was not associated with an increased risk of severe postoperative morbidity in our series. Colorectal Disease
© 2019 The Association of Coloproctology of Great Britain and Ireland.

Entities:  

Keywords:  Crohn's disease; laparoscopic; outcomes; recurrence; surgery

Year:  2019        PMID: 30659742     DOI: 10.1111/codi.14562

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  4 in total

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Authors:  G Pellino; D S Keller; G M Sampietro; V Annese; M Carvello; V Celentano; C Coco; F Colombo; N Cracco; F Di Candido; M Franceschi; S Laureti; G Mattioli; L Pio; G Sciaudone; G Sica; V Villanacci; R Zinicola; S Leone; S Danese; A Spinelli; G Delaini; F Selvaggi
Journal:  Tech Coloproctol       Date:  2020-01-25       Impact factor: 3.781

2.  Risk factors and predictors of 30-day complications and conversion to open surgery after repeat ileocolic resection of Crohn's disease.

Authors:  Sameh Hany Emile; Michael R Freund; Nir Horesh; Zoe Garoufalia; Rachel Gefen; Emanuela Silva-Alvarenga; Steven D Wexner
Journal:  Surg Endosc       Date:  2022-09-06       Impact factor: 3.453

3.  The safety and feasibility of laparoscopic redo surgery for recurrent Crohn's disease: A comparative clinical study of over 100 consecutive patients.

Authors:  Takayuki Ogino; Yuki Sekido; Tsuyoshi Hata; Norikatsu Miyoshi; Hidekazu Takahashi; Mamoru Uemura; Hirofumi Yamamoto; Yuichiro Doki; Hidetoshi Eguchi; Tsunekazu Mizushima
Journal:  Ann Gastroenterol Surg       Date:  2021-12-16

4.  Repeated surgery for recurrent Crohn's disease: does the outcome keep worsening operation after operation? A comparative study of 1224 consecutive procedures.

Authors:  Francesco Colombo; Alice Frontali; Caterina Baldi; Maria Cigognini; Giulia Lamperti; Carlo A Manzo; Giovanni Maconi; Sandro Ardizzone; Diego Foschi; Gianluca M Sampietro
Journal:  Updates Surg       Date:  2021-11-01
  4 in total

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