Literature DB >> 30659711

Rapid remission of Stevens-Johnson syndrome by combination therapy using etanercept and intravenous immunoglobulin and a review of the literature.

Ruojun Wang1,2,3, Shaomin Zhong1,2, Ping Tu1,2, Ruoyu Li1,2,3, Mingyue Wang1,2.   

Abstract

Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) are spectrum of rare, acute, and life-threatening delayed-type drug hypersensitivity reactions that are associated with high mortality rates. However, no therapeutic standard has been proposed for SJS/TEN. Here, we report a case of a patient diagnosed with Stevens-Johnson syndrome whose disease progression was halted by a single dose of etanercept and was treated successfully. In addition, we reviewed the literature reporting patients with SJS/TEN treated with similar regimens.
© 2019 Wiley Periodicals, Inc.

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Keywords:  Stevens-Johnson syndrome; etanercept; toxic epidermal necrolysis; treatment

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Year:  2019        PMID: 30659711     DOI: 10.1111/dth.12832

Source DB:  PubMed          Journal:  Dermatol Ther        ISSN: 1396-0296            Impact factor:   2.851


  1 in total

1.  Vesiculobullous Diseases.

Authors:  Simo Huang; Sylvia Hsu; Kiran Motaparthi
Journal:  Medicina (Kaunas)       Date:  2022-01-26       Impact factor: 2.430

  1 in total

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