Literature DB >> 30659455

Progress in Treatment of Gout Using Chinese and Western Medicine.

Xiang Wang1, Yan-Gang Wang2.   

Abstract

Gout is a crystal-related arthropathy resulting from the deposition of monosodium urate. Identifying appropriate treatments and novel drugs to decrease serum uric acid (SUA) levels and gout risk has been a major focus. By performing extensive literature review on the pathogenesis and Chinese and Western medicine treatment of gout, this paper aimed to identify novel targets for effective control of acute gout attacks and long-term reduction of SUA. In addition, we aimed to provide new directions for the improvement of therapeutic measures and the development of drugs. Although Western medicine can significantly contribute to the treatment of gout, Chinese herbal medicine has unique advantages, including reduced adverse reactions and higher patient compliance. It may also fill in the shortcomings of Western medicine in the intermittent period treatment of gout. In addition to constantly exploring pathogenesis and drug targets, research on Chinese herbal medicine is equally important. The combination of Chinese and Western medicine has proven to become an important direction for gout treatment.

Entities:  

Keywords:  Chinese medicine; Western medicine; gout therapy; research progress

Mesh:

Substances:

Year:  2019        PMID: 30659455     DOI: 10.1007/s11655-019-3058-y

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  17 in total

1.  Spontaneous resolution of acute gouty arthritis is associated with rapid induction of the anti-inflammatory factors TGFβ1, IL-10 and soluble TNF receptors and the intracellular cytokine negative regulators CIS and SOCS3.

Authors:  Yu-Hsuan Chen; Song-Chou Hsieh; Wei-Yu Chen; Ko-Jen Li; Cheng-Han Wu; Po-Chang Wu; Chang-Youh Tsai; Chia-Li Yu
Journal:  Ann Rheum Dis       Date:  2011-05-25       Impact factor: 19.103

Review 2.  Inflammasomes: mechanism of assembly, regulation and signalling.

Authors:  Petr Broz; Vishva M Dixit
Journal:  Nat Rev Immunol       Date:  2016-06-13       Impact factor: 53.106

3.  The Pharmacodynamics, Pharmacokinetics, and Safety of Arhalofenate in Combination with Febuxostat When Treating Hyperuricemia Associated with Gout.

Authors:  Alexandra S Steinberg; Bradley D Vince; Yun-Jung Choi; Robert L Martin; Charles A McWherter; Pol F Boudes
Journal:  J Rheumatol       Date:  2016-12-15       Impact factor: 4.666

4.  Effect of sodium alginate addition to resveratrol on acute gouty arthritis.

Authors:  Peng Wang; Dunlin Ren; Ying Chen; Meiju Jiang; Robin Wang; Yan-Gang Wang
Journal:  Cell Physiol Biochem       Date:  2015-04-30

5.  Anti-hyperuricemia effects of allopurinol are improved by Smilax riparia, a traditional Chinese herbal medicine.

Authors:  Xiao-Hui Wu; Chong-Zhi Wang; Shu-Qing Wang; Chao Mi; Yi He; Jun Zhang; Yan-Wen Zhang; Samantha Anderson; Chun-Su Yuan
Journal:  J Ethnopharmacol       Date:  2015-01-21       Impact factor: 4.360

Review 6.  Chinese herbal medicine for gout: a systematic review of randomized clinical trials.

Authors:  Xin-Xue Li; Mei Han; Yu-Yi Wang; Jian-Ping Liu
Journal:  Clin Rheumatol       Date:  2013-05-11       Impact factor: 2.980

Review 7.  Gout: joints and beyond, epidemiology, clinical features, treatment and co-morbidities.

Authors:  Philip C Robinson; Simon Horsburgh
Journal:  Maturitas       Date:  2014-05-14       Impact factor: 4.342

Review 8.  Emerging therapies for gout.

Authors:  N Lawrence Edwards; Alexander So
Journal:  Rheum Dis Clin North Am       Date:  2014-02-20       Impact factor: 2.670

9.  [Stage-based treatment of gouty arthritis by combination therapy of traditional Chinese and Western medicines: a randomized controlled trial].

Authors:  Yi-fei Wang; Bo-hua Li; Ming Zhang; Wen-bin Xu; Rong Zhou; Min Zhou
Journal:  Zhong Xi Yi Jie He Xue Bao       Date:  2008-06

10.  The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.

Authors:  Yun-Hee Youm; Kim Y Nguyen; Ryan W Grant; Emily L Goldberg; Monica Bodogai; Dongin Kim; Dominic D'Agostino; Noah Planavsky; Christopher Lupfer; Thirumala D Kanneganti; Seokwon Kang; Tamas L Horvath; Tarek M Fahmy; Peter A Crawford; Arya Biragyn; Emad Alnemri; Vishwa Deep Dixit
Journal:  Nat Med       Date:  2015-02-16       Impact factor: 53.440

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  3 in total

1.  Exploring the mechanism of action of dapansutrile in the treatment of gouty arthritis based on molecular docking and molecular dynamics.

Authors:  Jun-Feng Cao; Mei Wu; Shengyan Chen; Hengxiang Xu; Yunli Gong; Lixin Zhang; Qilan Zhang; Xiao Zhang
Journal:  Front Physiol       Date:  2022-08-29       Impact factor: 4.755

2.  Anti-inflammation effects of the total saponin fraction from Dioscorea nipponica Makino on rats with gouty arthritis by influencing MAPK signalling pathway.

Authors:  Qi Zhou; Hui Juan Sun; Shu Min Liu; Xi Hong Jiang; Qiu Yue Wang; Shuang Zhang; Dong Hua Yu
Journal:  BMC Complement Med Ther       Date:  2020-08-25

3.  Effect of Berberine on Hyperuricemia and Kidney Injury: A Network Pharmacology Analysis and Experimental Validation in a Mouse Model.

Authors:  Qiaoping Li; Ziwei Huang; Defu Liu; Jingna Zheng; Jianhui Xie; Jiannan Chen; Huifang Zeng; Ziren Su; Yucui Li
Journal:  Drug Des Devel Ther       Date:  2021-07-27       Impact factor: 4.162

  3 in total

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