Literature DB >> 30659003

Immune thrombocytopenic purpura presenting with spontaneous gingival haemorrhage in pregnancy.

Louise Dunphy1, Rhodri Williams2.   

Abstract

Gingival bleeding is a common intraoral finding, typically associated with inflamed tissues and periodontal disease. It is easily provoked by periodontal probing or toothbrushing. Spontaneous gingival bleeding rarely occurs and may be the only sign of systemic bleeding problems such as thrombocytopenia, leukaemia or coagulopathy. In pregnancy, acute onset of thrombocytopenia may occur in systemic disorders such as severe pre-eclampsia, HELLP syndrome (haemolysis, elevated liver enzymes, low platelets) or the acute fatty liver of pregnancy. The diagnosis and management of such conditions may challenge physicians. It requires a systematic approach with a comprehensive history to exclude causes of gingival haemorrhage such as periodontal disease, anticoagulant therapy, maxillofacial trauma, haematological disorders or a bacterial infection. The authors describe a case of immune thrombocytopenic purpura presenting with spontaneous gingival haemorrhage in pregnancy. This case highlights the fact that medical intervention to correct the underlying aberration of haemostasis is necessary for local measures to stop the gingival bleeding successfully. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  dentistry and oral medicine; haematology (drugs and medicines)

Mesh:

Substances:

Year:  2019        PMID: 30659003      PMCID: PMC6340514          DOI: 10.1136/bcr-2018-228309

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  15 in total

1.  Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group.

Authors:  Francesco Rodeghiero; Roberto Stasi; Terry Gernsheimer; Marc Michel; Drew Provan; Donald M Arnold; James B Bussel; Douglas B Cines; Beng H Chong; Nichola Cooper; Bertrand Godeau; Klaus Lechner; Maria Gabriella Mazzucconi; Robert McMillan; Miguel A Sanz; Paul Imbach; Victor Blanchette; Thomas Kühne; Marco Ruggeri; James N George
Journal:  Blood       Date:  2008-11-12       Impact factor: 22.113

Review 2.  Effect of pregnancy on periodontal and dental health.

Authors:  Merja Anneli Laine
Journal:  Acta Odontol Scand       Date:  2002-10       Impact factor: 2.331

3.  Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy.

Authors:  Dongmei Sun; Nadine Shehata; Xiang Y Ye; Sandra Gregorovich; Bryon De France; Donald M Arnold; Prakesh S Shah; Ann Kinga Malinowski
Journal:  Blood       Date:  2016-07-11       Impact factor: 22.113

Review 4.  How I treat thrombocytopenia in pregnancy.

Authors:  Terry Gernsheimer; Andra H James; Roberto Stasi
Journal:  Blood       Date:  2012-11-13       Impact factor: 22.113

Review 5.  Management of idiopathic thrombocytopenic purpura in pregnancy.

Authors:  K K Gill; J G Kelton
Journal:  Semin Hematol       Date:  2000-07       Impact factor: 3.851

6.  Splenectomy during pregnancy: treatment of refractory immune thrombocytopenic purpura.

Authors:  Reeta Mahey; Simran Deep Kaur; Sunil Chumber; Alka Kriplani; Neerja Bhatla
Journal:  BMJ Case Rep       Date:  2013-12-20

Review 7.  Management of immune thrombocytopenic purpura in adults.

Authors:  Roberto Stasi; Drew Provan
Journal:  Mayo Clin Proc       Date:  2004-04       Impact factor: 7.616

8.  Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes.

Authors:  Marie Scully; Mari Thomas; Mary Underwood; Henry Watson; Katherine Langley; Raymond S Camilleri; Amanda Clark; Desmond Creagh; Rachel Rayment; Vickie Mcdonald; Ashok Roy; Gillian Evans; Siobhan McGuckin; Fionnuala Ni Ainle; Rhona Maclean; William Lester; Michael Nash; Rosemary Scott; Patrick O Brien
Journal:  Blood       Date:  2014-05-23       Impact factor: 22.113

9.  Immune thrombocytopenic purpura presenting as unprovoked gingival hemorrhage: a case report.

Authors:  Mehmet V Bal; Cenker Z Koyuncuoglu; Işıl Saygun
Journal:  Open Dent J       Date:  2014-09-29

10.  Significance of periodontal health in primary immune thrombocytopenia- a case report and review of literature.

Authors:  Aditi Sangwan; Shikha Tewari; Satish C Narula; Rajinder K Sharma; Pankaj Sangwan
Journal:  J Dent (Tehran)       Date:  2013-03-31
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